Skin-inspired, open mesh electrochemical sensors for lactate and oxygen monitoring

被引：66

作者：

Ashley, Brandon K. ^{[1
]}

Brown, Matthew S. ^{[1
]}

Park, Youjoong ^{[1
]}

Kuan, Sally ^{[1
]}

Koh, Ahyeon ^{[1
]}

机构：

[1] SUNY Binghamton, Dept Biomed Engn, Binghamton, NY 13902 USA

来源：

BIOSENSORS & BIOELECTRONICS | 2019年 / 132卷

关键词：

Deterministic geometries; Mechanically conformable; Porous; Wearable electronics; Lactate sensor; Oxygen sensor; STRETCHABLE ELECTRONICS; CARBON NANOTUBES; ON-SKIN; BIOSENSOR; STRATEGIES; DEVICES; ARRAYS;

D O I：

10.1016/j.bios.2019.02.041

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Research in wearable electronics has paved the way for next-generation technology, sought to create point-of care biosensors that combine chemical sensing on a biocompatible platform with a broad range of applications in human health monitoring. Despite significant progress, the microspatial mechanical mismatch and fluid-impermeable interface presented between skin and the electronics create adscititious problems in device lamination, conformality, and long-term monitoring. Herein, we engineered a skin-inspired, deterministically patterned, electrochemical biosensor that can be fully integrated with the curvilinear surface of the human body, while mechanically adapting to the natural stresses applied to the skin and allowing the mass transfer of gas and fluids. In particular, we developed mechanically-compliant lattice-structured biosensors for the continuous evaluation of lactate and oxygen. Systematic studies of the sensor performance were evaluated with variations in polymeric membranes and its ability to withstand commonplace harsh, multiaxial stresses.

引用

页码：343 / 351

页数：9

共 60 条

[11] Bioinspired Interlocked and Hierarchical Design of ZnO Nanowire Arrays for Static and Dynamic Pressure-Sensitive Electronic Skins [J].

Ha, Minjeong ;

Lim, Seongdong ;

Park, Jonghwa ;

Um, Doo-Seung ;

Lee, Youngoh ;

Ko, Hyunhyub .

ADVANCED FUNCTIONAL MATERIALS, 2015, 25 (19) :2841-2849

[12] Multifunctional Skin-Like Electronics for Quantitative, Clinical Monitoring of Cutaneous Wound Healing [J].

Hattori, Yoshiaki ;

Falgout, Leo ;

Lee, Woosik ;

Jung, Sung-Young ;

Poon, Emily ;

Lee, Jung Woo ;

Na, Ilyoun ;

Geisler, Amelia ;

Sadhwani, Divya ;

Zhang, Yihui ;

Su, Yewang ;

Wang, Xiaoqi ;

Liu, Zhuangjian ;

Xia, Jing ;

Cheng, Huanyu ;

Webb, R. Chad ;

Bonifas, Andrew P. ;

Won, Philip ;

Jeong, Jae-Woong ;

Jang, Kyung-In ;

Song, Young Min ;

Nardone, Beatrice ;

Nodzenski, Michael ;

Fan, Jonathan A. ;

Huang, Yonggang ;

West, Dennis P. ;

Paller, Amy S. ;

Alam, Murad ;

Yeo, Woon-Hong ;

Rogers, John A. .

ADVANCED HEALTHCARE MATERIALS, 2014, 3 (10) :1597-1607

[13] Wearable sensors: modalities, challenges, and prospects [J].

Heikenfeld, J. ;

Jajack, A. ;

Rogers, J. ;

Gutruf, P. ;

Tian, L. ;

Pan, T. ;

Li, R. ;

Khine, M. ;

Kim, J. ;

Wang, J. ;

Kim, J. .

LAB ON A CHIP, 2018, 18 (02) :217-248

[14]

Holzapfel G. A., 2001, HDB MAT BEHAV MODELS, V3, P1049, DOI [10.1016/B978-012443341-0/50107-1, DOI 10.1016/B978-012443341-0/50107-1]

[15] Skin-inspired highly stretchable and conformable matrix networks for multifunctional sensing [J].

Hua, Qilin ;

Sun, Junlu ;

Liu, Haitao ;

Bao, Rongrong ;

Yu, Ruomeng ;

Zhai, Junyi ;

Pan, Caofeng ;

Wang, Zhong Lin .

NATURE COMMUNICATIONS, 2018, 9

[16] A Physically Transient Form of Silicon Electronics [J].

Hwang, Suk-Won ;

Tao, Hu ;

Kim, Dae-Hyeong ;

Cheng, Huanyu ;

Song, Jun-Kyul ;

Rill, Elliott ;

Brenckle, Mark A. ;

Panilaitis, Bruce ;

Won, Sang Min ;

Kim, Yun-Soung ;

Song, Young Min ;

Yu, Ki Jun ;

Ameen, Abid ;

Li, Rui ;

Su, Yewang ;

Yang, Miaomiao ;

Kaplan, David L. ;

Zakin, Mitchell R. ;

Slepian, Marvin J. ;

Huang, Yonggang ;

Omenetto, Fiorenzo G. ;

Rogers, John A. .

SCIENCE, 2012, 337 (6102) :1640-1644

[17] A wearable chemical-electrophysiological hybrid biosensing system for real-time health and fitness monitoring [J].

Imani, Somayeh ;

Bandodkar, Amay J. ;

Mohan, A. M. Vinu ;

Kumar, Rajan ;

Yu, Shengfei ;

Wang, Joseph ;

Mercier, Patrick P. .

NATURE COMMUNICATIONS, 2016, 7

[18] Soft network composite materials with deterministic and bio-inspired designs [J].

Jang, Kyung-In ;

Chung, Ha Uk ;

Xu, Sheng ;

Lee, Chi Hwan ;

Luan, Haiwen ;

Jeong, Jaewoong ;

Cheng, Huanyu ;

Kim, Gwang-Tae ;

Han, Sang Youn ;

Lee, Jung Woo ;

Kim, Jeonghyun ;

Cho, Moongee ;

Miao, Fuxing ;

Yang, Yiyuan ;

Jung, Han Na ;

Flavin, Matthew ;

Liu, Howard ;

Kong, Gil Woo ;

Yu, Ki Jun ;

Rhee, Sang Il ;

Chung, Jeahoon ;

Kim, Byunggik ;

Kwak, Jean Won ;

Yun, Myoung Hee ;

Kim, Jin Young ;

Song, Young Min ;

Paik, Ungyu ;

Zhang, Yihui ;

Huang, Yonggang ;

Rogers, John A. .

NATURE COMMUNICATIONS, 2015, 6

[19] Rugged and breathable forms of stretchable electronics with adherent composite substrates for transcutaneous monitoring [J].

Jang, Kyung-In ;

Han, Sang Youn ;

Xu, Sheng ;

Mathewson, Kyle E. ;

Zhang, Yihui ;

Jeong, Jae-Woong ;

Kim, Gwang-Tae ;

Webb, Chad ;

Lee, Jung Woo ;

Dawidczyk, Thomas J. ;

Kim, Rak Hwan ;

Song, Young Min ;

Yeo, Woon-Hong ;

Kim, Stanley ;

Cheng, Huanyu ;

Rhee, Sang Il ;

Chung, Jeahoon ;

Kim, Byunggik ;

Chung, Ha Uk ;

Lee, Dongjun ;

Yang, Yiyuan ;

Cho, Moongee ;

Gaspar, John G. ;

Carbonari, Ronald ;

Fabiani, Monica ;

Gratton, Gabriele ;

Huang, Yonggang ;

Rogers, John A. .

NATURE COMMUNICATIONS, 2014, 5

[20] Capacitive Epidermal Electronics for Electrically Safe, Long-Term Electrophysiological Measurements [J].

Jeong, Jae-Woong ;

Kim, Min Ku ;

Cheng, Huanyu ;

Yeo, Woon-Hong ;

Huang, Xian ;

Liu, Yuhao ;

Zhang, Yihui ;

Huang, Yonggang ;

Rogers, John A. .

ADVANCED HEALTHCARE MATERIALS, 2014, 3 (05) :642-648

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