China Brain Project: Basic Neuroscience, Brain Diseases, and Brain-Inspired Computing

被引:232
作者
Poo, Mu-ming [1 ,2 ]
Du, Jiu-lin [1 ,2 ]
Ip, Nancy Y. [3 ,4 ]
Xiong, Zhi-Qi [1 ,2 ]
Xu, Bo [2 ,5 ]
Tan, Tieniu [2 ,5 ]
机构
[1] Chinese Acad Sci, Inst Neurosci, Shanghai 200031, Peoples R China
[2] CAS Ctr Excellence Brain Sci & Intelligence Techn, Shanghai 200031, Peoples R China
[3] Hong Kong Univ Sci & Technol, Div Life Sci, Hong Kong, Hong Kong, Peoples R China
[4] Hong Kong Univ Sci & Technol, State Key Lab Mol Neurosci, Hong Kong, Hong Kong, Peoples R China
[5] Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China
关键词
PRIMATES; MODELS;
D O I
10.1016/j.neuron.2016.10.050
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The China Brain Project covers both basic research on neural mechanisms underlying cognition and translational research for the diagnosis and intervention of brain diseases as well as for brain-inspired intelligence technology. We discuss some emerging themes, with emphasis on unique aspects.
引用
收藏
页码:591 / 596
页数:6
相关论文
共 18 条
[1]   Epidemiology of Alzheimer's disease and other forms of dementia in China, 1990-2010: a systematic review and analysis [J].
Chan, Kit Yee ;
Wang, Wei ;
Wu, Jing Jing ;
Liu, Li ;
Theodoratou, Evropi ;
Car, Josip ;
Middleton, Lefkos ;
Russ, Tom C. ;
Deary, Ian J. ;
Campbell, Harry ;
Wang, Wei ;
Rudan, Igor .
LANCET, 2013, 381 (9882) :2016-2023
[2]   Genome editing in nonhuman primates: approach to generating human disease models [J].
Chen, Y. ;
Niu, Y. ;
Ji, W. .
JOURNAL OF INTERNAL MEDICINE, 2016, 280 (03) :246-251
[3]   Mouse eggs made from skin cells in a dish [J].
David Cyranoski .
Nature, 2016, 538 (7625) :301-301
[4]   Angiogenesis: from plants to blood vessels [J].
Fan, Tai-Ping ;
Yeh, Ju-Ching ;
Leung, Kar Wah ;
Yue, Patrick Y. K. ;
Wong, Ricky N. S. .
TRENDS IN PHARMACOLOGICAL SCIENCES, 2006, 27 (06) :297-309
[5]   Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimer's disease [J].
Fu, Amy K. Y. ;
Hung, Kwok-Wang ;
Huang, Huiqian ;
Gu, Shuo ;
Shen, Yang ;
Cheng, Elaine Y. L. ;
Ip, Fanny C. F. ;
Huang, Xuhui ;
Fu, Wing-Yu ;
Ip, Nancy Y. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (27) :9959-9964
[6]  
Goodfellow I. J., 2014, ADV NEURAL INFORM PR, P2672
[7]   The connectivity map: Using gene-expression signatures to connect small molecules, genes, and disease [J].
Lamb, Justin ;
Crawford, Emily D. ;
Peck, David ;
Modell, Joshua W. ;
Blat, Irene C. ;
Wrobel, Matthew J. ;
Lerner, Jim ;
Brunet, Jean-Philippe ;
Subramanian, Aravind ;
Ross, Kenneth N. ;
Reich, Michael ;
Hieronymus, Haley ;
Wei, Guo ;
Armstrong, Scott A. ;
Haggarty, Stephen J. ;
Clemons, Paul A. ;
Wei, Ru ;
Carr, Steven A. ;
Lander, Eric S. ;
Golub, Todd R. .
SCIENCE, 2006, 313 (5795) :1929-1935
[8]   Autism-like behaviours and germline transmission in transgenic monkeys overexpressing MeCP2 [J].
Liu, Zhen ;
Li, Xiao ;
Zhang, Jun-Tao ;
Cai, Yi-Jun ;
Cheng, Tian-Lin ;
Cheng, Cheng ;
Wang, Yan ;
Zhang, Chen-Chen ;
Nie, Yan-Hong ;
Chen, Zhi-Fang ;
Bian, Wen-Jie ;
Zhang, Ling ;
Xiao, Jianqiu ;
Lu, Bin ;
Zhang, Yue-Fang ;
Zhang, Xiao-Di ;
Sang, Xiao ;
Wu, Jia-Jia ;
Xu, Xiu ;
Xiong, Zhi-Qi ;
Zhang, Feng ;
Yu, Xiang ;
Gong, Neng ;
Zhou, Wen-Hao ;
Sun, Qiang ;
Qiu, Zilong .
NATURE, 2016, 530 (7588) :98-+
[9]   Generation of macaques with sperm derived from juvenile monkey testicular xenografts [J].
Liu, Zhen ;
Nie, Yan-Hong ;
Zhang, Chen-Chen ;
Cai, Yi-Jun ;
Wang, Yan ;
Lu, Hui-Ping ;
Li, Yu-Zhuo ;
Cheng, Cheng ;
Qiu, Zi-Long ;
Sun, Qiang .
CELL RESEARCH, 2016, 26 (01) :139-142
[10]  
Marblestone A., 2016, ARXIV160603813V1