Is continuous positive airway pressure (CPAP) a new standard of care for type 1 respiratory failure in COVID-19 patients? A retrospective observational study of a dedicated COVID-19 CPAP service

被引:55
作者
Nightingale, Rebecca [1 ,2 ]
Nwosu, Nneka [2 ]
Kutubudin, Farheen [2 ]
Fletcher, Tom [1 ,2 ]
Lewis, Joe [1 ,2 ]
Frost, Frederick [2 ]
Haigh, Kathryn [2 ]
Robinson, Ryan [1 ,2 ]
Kumar, Ayesha [2 ]
Jones, Gareth [2 ]
Brown, Deborah [2 ]
Abouyannis, Michael [1 ,2 ,3 ]
Beadsworth, Mike [1 ,2 ]
Hampshire, Peter [2 ]
Aston, Stephen [2 ,3 ]
Gautam, Manish [2 ]
Burhan, Hassan [2 ]
机构
[1] Univ Liverpool Liverpool Sch Trop Med, Dept Clin Sci, Liverpool, Merseyside, England
[2] Liverpool Univ Hosp NHS Fdn Trust, Dept Resp Med, Trop & Infect Dis Unit, Intens Care Unit, Liverpool, Merseyside, England
[3] Univ Liverpool, Inst Infect & Global Hlth, Liverpool, Merseyside, England
关键词
respiratory Infection; non invasive ventilation;
D O I
10.1136/bmjresp-2020-000639
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
The aim of this case series is to describe and evaluate our experience of continuous positive airway pressure (CPAP) to treat type 1 respiratory failure in patients with COVID-19. CPAP was delivered in negative pressure rooms in the newly repurposed infectious disease unit. We report a cohort of 24 patients with type 1 respiratory failure and COVID-19 admitted to the Royal Liverpool Hospital between 1 April and 30 April 2020. Overall, our results were positive; we were able to safely administer CPAP outside the walls of a critical care or high dependency unit environment and over half of patients (58%) avoided mechanical ventilation and a total of 19 out of 24 (79%) have survived and been discharged from our care.
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