Retinal oxygen saturation and metabolism: how does it pertain to glaucoma? An update on the application of retinal oximetry in glaucoma

被引：17

作者：

Tobe, Leslie A. ^{[1
]}

Harris, Alon ^{[1
]}

Schroeder, Anne ^{[1
]}

Gerber, Austin ^{[1
]}

Holland, Stephen ^{[1
]}

Amireskandari, Annahita ^{[1
]}

Kim, Nathaniel J. ^{[1
]}

Siesky, Brent ^{[1
]}

机构：

[1] Indiana Univ Sch Med, Dept Ophthalmol, Indianapolis, IN 46202 USA

来源：

EUROPEAN JOURNAL OF OPHTHALMOLOGY | 2013年 / 23卷 / 04期

关键词：

Blood flow; Glaucoma; Oxygen saturation; Retinal oximetry; OCULAR BLOOD-FLOW; NITRIC-OXIDE; DORZOLAMIDE; VESSELS; REFLECTANCE;

D O I：

10.5301/ejo.5000289

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Purpose: To discuss the techniques and mechanisms of retinal oximetry with a focus on utilization of retinal oximetry in the assessment of retinal oxygen saturation in glaucoma. Methods: We reviewed recent literature found by searching combinations of the following search terms: glaucoma, retinal oximetry, ocular blood flow, retinal blood flow, oxygen saturation. We also reviewed pertinent references from articles found in this search. Results: Retinal oximetry offers the potential for directly assessing oxygen saturation in retinal tissue. This capability can contribute to the knowledge of ocular blood flow and its role in the pathogenesis of glaucoma. Conclusions: Recent research has shown that retinal oximetry could become an important clinical tool in glaucoma. However, more research is needed to validate the reliability and reproducibility of retinal oximetry, and to fully deduce its clinical role in ocular diseases.

引用

页码：465 / 472

页数：8

共 46 条

[21] Oxygen saturation levels in the juxta-papillary retina in eyes with glaucoma [J].

Ito, Marni ;

Murayama, Koichiro ;

Deguchi, Tatsuya ;

Takasu, Masayuki ;

Gil, Tamir ;

Araie, Makoto ;

Peyman, Gholam ;

Yoneya, Shin .

EXPERIMENTAL EYE RESEARCH, 2008, 86 (03) :512-518

[22] Snapshot hyperspectral imaging in ophthalmology [J].

Johnson, William R. ;

Wilson, Daniel W. ;

Fink, Wolfgang ;

Humayun, Mark ;

Bearman, Greg .

JOURNAL OF BIOMEDICAL OPTICS, 2007, 12 (01)

[23] Spectral oximetry assessed with high-speed ultra-high-resolution optical coherence tomography [J].

Kagemann, Larry ;

Wollstein, Gadi ;

Wojtkowski, Maciej ;

Ishikawa, Hiroshi ;

Townsend, Kelly A. ;

Gabriele, Michelle L. ;

Srinivasan, Vivek J. ;

Fujimoto, James G. ;

Schuman, Joel S. .

JOURNAL OF BIOMEDICAL OPTICS, 2007, 12 (04)

[24]

KRAMER KURT, 1951, AMER JOUR PHYSIOL, V165, P229

[25]

LAING RA, 1975, INVEST OPHTH VISUAL, V14, P606

[26]

LAMBERT JH, 1892, KLASSIKER EXAKTEN WI, P31

[27] Intravascular oxygen saturation in retinal vessels in normal subjects and open-angle glaucoma subjects [J].

Michelson, Georg ;

Scibor, Mateusz .

ACTA OPHTHALMOLOGICA SCANDINAVICA, 2006, 84 (03) :289-295

[28]

Moore D, 2008, CLIN OPHTHALMOL, V2, P849

[29] Retinal Oximetry in Primary Open-Angle Glaucoma [J].

Olafsdottir, Olof Birna ;

Hardarson, Sveinn Hakon ;

Gottfredsdottir, Maria Soffia ;

Harris, Alon ;

Stefansson, Einar .

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2011, 52 (09) :6409-6413

[30] Retinal Oximetry Images Must Be Standardized: A Methodological Analysis [J].

Palsson, Olafur ;

Geirsdottir, Asbjorg ;

Hardarson, Sveinn Hakon ;

Olafsdottir, Olof Birna ;

Kristjansdottir, Jona Valgerdur ;

Stefansson, Einar .

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2012, 53 (04) :1729-1733

← 1 2 3 4 5 →