Kidney function and other factors and their association with falls updates The screening for CKD among older people across Europe (SCOPE) study

被引：5

作者：

Britting, Sabine ^{[1
]}

Artzi-Medvedik, Rada ^{[2
]}

Fabbietti, Paolo ^{[3
,4
]}

Tap, Lisanne ^{[5
]}

Mattace-Raso, Francesco ^{[5
]}

Corsonello, Andrea ^{[3
]}

Lattanzio, Fabrizia ^{[3
]}

Arnlov, Johan ^{[6
,7
,8
]}

Carlsson, Axel C. ^{[6
,7
]}

Roller-Wirnsberger, Regina ^{[9
]}

Wirnsberger, Gerhard ^{[10
]}

Kostka, Tomasz ^{[11
]}

Guligowska, Agnieszka ^{[11
]}

Formiga, Francesc ^{[12
]}

Moreno-Gonzalez, Rafael ^{[12
]}

Gil, Pedro ^{[13
]}

Martinez, Sara Lainez ^{[13
]}

Kob, Robert ^{[1
]}

Melzer, Itshak ^{[14
]}

Freiberger, Ellen ^{[1
]}

机构：

[1] Friedrich Alexander Univ Erlangen Nurnberg, Inst Biomed Aging IBA, Dept Internal Med Geriatr, Erlangen, Germany

[2] Ben Gurion Univ Negev, Recanati Sch Community Hlth Profess, Dept Nursing, Fac Hlth Sci, Beer Sheva, Israel

[3] Italian Natl Res Ctr Aging IRCCS INRCA, Ancona, Italy

[4] IRCCS INRCA, Lab Geriatr Pharmacoepidemiol & Biostat, Via S Margherita 5, I-60124 Ancona, Italy

[5] Erasmus MC, Dept Internal Med, Geriatr Med Sect, Rotterdam, Netherlands

[6] Uppsala Univ, Dept Med Sci, Uppsala, Sweden

[7] Karolinska Inst, Div Family Med, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden

[8] Dalarna Univ, Sch Hlth & Social Studies, Falun, Sweden

[9] Med Univ Graz, Dept Internal Med Geriatr, Graz, Austria

[10] Med Univ Graz, Dept Internal Med, Div Nephrol, Graz, Austria

[11] Med Univ Lodz, Dept Geriatr, Hlth Ageing Res Ctr, Lodz, Poland

[12] Bellvitge Univ Hosp, IDIBELL, Geriatr Unit, Dept Internal Med, Barcelona, Spain

[13] Hosp Clin San Carlos, Geriatr Dept, Martin Lagos S-N, Madrid 28040, Spain

[14] Ben Gurion Univ Negev, Dept Phys Therapy, Recanati Sch Community Hlth Profess, Fac Hlth Sci, Beer Sheva, Israel

来源：

BMC GERIATRICS | 2020年 / 20卷 / Suppl 1期

基金：

欧盟地平线“2020”;

关键词：

Kidney function; Older people; Falls; Injurious falls; Fear of falling; Urinary incontinence; URINARY-TRACT SYMPTOMS; RISK-FACTORS; INJURIOUS FALLS; INCONTINENCE; FEAR; ADULTS; CONSEQUENCES; PREVALENCE; VALIDATION; FRACTURES;

D O I：

10.1186/s12877-020-01698-2

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Background: Reduced kidney function has become a major public health concern, especially among older people, as Chronic Kidney Disease (CKD) is associated with increased risk of end stage renal disease and mortality. Falls are a serious negative health outcome in older persons with one third of people aged 65 years experiencing a fall per year and increasing fall rates with increasing age. The impact of CKD on falls in older community-dwelling persons is not well investigated. Additionally, lower urinary tract symptoms (LUTS) may also increase the risk of falls. Therefore, our aim was to investigate the impact of CKD and LUTS on falls as well as on injurious falls. Methods: The SCOPE study is an observational, multinational, multicenter, prospective cohort study involving communitydwelling older persons aged 75 years and more recruited from August 2016 to March 2018 in seven European countries. The main outcomes of the present study were any falls and any injurious falls during the 12 months before enrolment The cross-sectional association of estimated glomerular filtration rate (eGFR) and LUIS with study outcomes was investigated by logistic regression analysis adjusted for baseline characteristics of enrolled subjects. Results: Our series consisted of 2256 SCOPE participants (median age = 795 years, 55.7% female). Of them, 746 participants experienced a fall and 484 reported an injurious fall in the 12 months prior to baseline assessment CKD was not significantly associated with falls (OR = 0.95, 95%CI = 0.79-1.14 for eGFR< 60; OR = 1.02, 95%CI = 0.81-128 for eGFR< 45; OR = 1.08, 95%CI = 0.74-1.57 for eGFR< 30) or injurious falls (OR = 0.91, 95%CI = 0.67-124 for eGFR< 60; OR = 0.93, 95%CI = 0.63-137 for eGFR< 45; OR = 1.19, 95%CI = 0.62-2.29 for eGFR< 30). LUTS were found significantly associated with both falls (OR = 156, 95960 =129-1.89) and injurious falls (OR = 158, 95%0 =1.14-2.19), and such associations were confirmed in all multivariable models. Conclusions: Cross-sectional data suggest that CKD may not be associated with history of falls or injurious falls, whereas LUTS is significantly associated with the outcomes.

引用

页数：10

共 45 条

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