Exploring associations between tumor mutational burden and tumor response in gynecologic malignancies

被引：0
作者：
Valente, Ana [1 ]
Essel, Kathleen Gong [1 ]
Ding, Kai [2 ]
Moore, Kathleen N. [2 ]
机构：
[1] Univ Oklahoma, Hlth Sci Ctr, Oklahoma City, OK USA
[2] Univ Oklahoma, Oklahoma City, OK USA
来源：
GYNECOLOGIC ONCOLOGY | 2020年 / 159卷 / 02期
关键词：
PD-1; BLOCKADE;
D O I：
10.1016/j.ygyno.2020.07.086
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
33
引用
收藏
页码：E35 / E35
页数：1
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  • [1] Comprehensive cancer-gene panels can be used to estimate mutational load and predict clinical benefit to PD-1 blockade in clinical practice
    Campesato, Luis Felipe
    Barroso-Sousa, Romualdo
    Jimenez, Leandro
    Correa, Bruna R.
    Sabbaga, Jorge
    Hoff, Paulo M.
    Reis, Luiz F. L.
    Galante, Pedro Alexandre F.
    Camargo, Anamaria A.
    [J]. ONCOTARGET, 2015, 6 (33) : 34221 - 34227
  • [2] Targeted Next Generation Sequencing Identifies Markers of Response to PD-1 Blockade
    Johnson, Douglas B.
    Frampton, Garrett M.
    Rioth, Matthew J.
    Yusko, Erik
    Xu, Yaomin
    Guo, Xingyi
    Ennis, Riley C.
    Fabrizio, David
    Chalmers, Zachary R.
    Greenbowe, Joel
    Ali, Siraj M.
    Balasubramanian, Sohail
    Sun, James X.
    He, Yuting
    Frederick, Dennie T.
    Puzanov, Igor
    Balko, Justin M.
    Cates, Justin M.
    Ross, Jeffrey S.
    Sanders, Catherine
    Robins, Harlan
    Shyr, Yu
    Miller, Vincent A.
    Stephens, Philip J.
    Sullivan, Ryan J.
    Sosman, Jeffrey A.
    Lovly, Christine M.
    [J]. CANCER IMMUNOLOGY RESEARCH, 2016, 4 (11) : 959 - 967
  • [3] PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
    Le, D. T.
    Uram, J. N.
    Wang, H.
    Bartlett, B. R.
    Kemberling, H.
    Eyring, A. D.
    Skora, A. D.
    Luber, B. S.
    Azad, N. S.
    Laheru, D.
    Biedrzycki, B.
    Donehower, R. C.
    Zaheer, A.
    Fisher, G. A.
    Crocenzi, T. S.
    Lee, J. J.
    Duffy, S. M.
    Goldberg, R. M.
    de la Chapelle, A.
    Koshiji, M.
    Bhaijee, F.
    Huebner, T.
    Hruban, R. H.
    Wood, L. D.
    Cuka, N.
    Pardoll, D. M.
    Papadopoulos, N.
    Kinzler, K. W.
    Zhou, S.
    Cornish, T. C.
    Taube, J. M.
    Anders, R. A.
    Eshleman, J. R.
    Vogelstein, B.
    Diaz, L. A., Jr.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2015, 372 (26) : 2509 - 2520
  • [4] Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
    Rizvi, Naiyer A.
    Hellmann, Matthew D.
    Snyder, Alexandra
    Kvistborg, Pia
    Makarov, Vladimir
    Havel, Jonathan J.
    Lee, William
    Yuan, Jianda
    Wong, Phillip
    Ho, Teresa S.
    Miller, Martin L.
    Rekhtman, Natasha
    Moreira, Andre L.
    Ibrahim, Fawzia
    Bruggeman, Cameron
    Gasmi, Billel
    Zappasodi, Roberta
    Maeda, Yuka
    Sander, Chris
    Garon, Edward B.
    Merghoub, Taha
    Wolchok, Jedd D.
    Schumacher, Ton N.
    Chan, Timothy A.
    [J]. SCIENCE, 2015, 348 (6230) : 124 - 128
  • [5] Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma
    Snyder, Alexandra
    Makarov, Vladimir
    Merghoub, Taha
    Yuan, Jianda
    Zaretsky, Jesse M.
    Desrichard, Alexis
    Walsh, Logan A.
    Postow, Michael A.
    Wong, Phillip
    Ho, Teresa S.
    Hollmann, Travis J.
    Bruggeman, Cameron
    Kannan, Kasthuri
    Li, Yanyun
    Elipenahli, Ceyhan
    Liu, Cailian
    Harbison, Christopher T.
    Wang, Lisu
    Ribas, Antoni
    Wolchok, Jedd D.
    Chan, Timothy A.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2014, 371 (23) : 2189 - 2199
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