Progressive multifocal leukoencephalopathy secondary to hepatitis C virus infection-related T-cell lymphopenia

被引：3

作者：

Aung, Ar Kar ^{[1
,2
,5
]}

Robinson, Jessica ^{[1
]}

Hey, Penelope ^{[6
]}

Lehmann, Mahalia ^{[1
]}

Chow, Yan ^{[7
]}

Stark, Richard J. ^{[3
,5
]}

Bosco, Julian J. ^{[4
]}

机构：

[1] Alfred Hosp, Dept Gen Med, Melbourne, Vic, Australia

[2] Alfred Hosp, Dept Infect Dis, Melbourne, Vic, Australia

[3] Alfred Hosp, Dept Neurol, Melbourne, Vic, Australia

[4] Alfred Hosp, Dept Allergy Immunol Resp Med, Melbourne, Vic, Australia

[5] Monash Univ, Melbourne, Vic, Australia

[6] Austin Hosp, Dept Gastroenterol & Hepatol, Melbourne, Vic, Australia

[7] Caulfield Hosp, Aged Care & Rehabil, Melbourne, Vic, Australia

来源：

INTERNAL MEDICINE JOURNAL | 2019年 / 49卷 / 01期

关键词：

progressive multifocal leukoencephalopathy; John-Cunningham virus; hepatitis C virus; lymphopenia; immune suppression; CD4(+); APOPTOSIS; IMPACT; JCV;

D O I：

10.1111/imj.14174

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Progressive multifocal leukoencephalopathy (PML) is an uncommon neurological condition known to occur in the setting of T-cell immune suppression. We report a case of hepatitis C virus (HCV) infection-related T-cell lymphopenia manifesting as PML. HCV treatment and transient viral suppression resulted in immunological recovery with clinical stabilisation.

引用

页码：114 / 118

页数：5

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