A case-based review of a simplified quantitative approach to acid-base analysis

被引：30

作者：

Hopper, Kate ^{[1
]}

Haskins, Steve C. ^{[1
]}

机构：

[1] Univ Calif Davis, Dept Vet Surg & Radiol Sci, Sch Vet Med, Davis, CA 95616 USA

来源：

JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE | 2008年 / 18卷 / 05期

关键词：

hypoproteinemia; lactic acidosis; metabolic acidosis; metabolic alkalosis;

D O I：

10.1111/j.1476-4431.2008.00344.x

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Objective - To present a simplified quantitative approach to acid-base analysis and to demonstrate its clinical utility. Data Sources - Original research articles and textbooks. Data Synthesis - A simplified quantitative approach to acid-base analysis is presented, which is derived from the Fencl-Stewart approach and calculates the magnitude of the effect on the standardized base excess (SBE) of 5 separate variables: (1) a free water effect (marked by sodium concentration), (2) an effect marked by the chloride concentration, (3) an albumin effect, (4) a lactate effect, and (5) a phosphate effect. Six clinical cases with acid-base abnormalities are presented in which the quantitative approach provides information that is not apparent from the traditional approach. Conclusion - This simplified quantitative approach provides a comprehensive evaluation of complex acid-base disorders, identifies individual processes and their relative influence on SBE, and aids in the development of an appropriate therapeutic plan.

引用

页码：467 / 476

页数：10

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