Studies on Ru(bipy)2dppx2+ as interacting mode spectroscopic probe of DNA

被引：0
|
作者：
Chen, F
He, ZK [1 ]
机构：
[1] Wuhan Univ, Coll Chem & Mol Sci, Wuhan 430072, Peoples R China
[2] Huazhong Univ Sci & Technol, Dept Chem, Wuhan 430074, Peoples R China
来源：
SPECTROSCOPY AND SPECTRAL ANALYSIS | 2005年 / 25卷 / 12期
关键词：
Ru(bipy)(2) dppx(2+); DNA; adriamycin; spectroscopic probe;
D O I：
暂无
中图分类号：
O433 [光谱学];
学科分类号：
0703 ; 070302 ;
摘要：
The interacting mode of adriamycin with DNA has been studied by the use of molecular "light switch" complex Ru(bipy)(2)-dppx(2+) as a interacting mode spectroscopic probe. The results of the influence of ADM on the fluorescence and Scatchard equation of Ru(bipy)(2)dppx(2+)-DNA system indicate that ADM intercalates the base pairs of DNA. Compared with normal DNA interacting mode spectroscopic probe EB, Ru(bipy)(2)dppx(2+) has the advantages of higher sensitivity, lower toxicity, higher stability and simplicity.
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收藏
页码：2052 / 2055
页数：4
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