A bioelectronic sensor based on canine olfactory nanovesicle-carbon nanotube hybrid structures for the fast assessment of food quality

被引:73
作者
Park, Juhun [2 ]
Lim, Jong Hyun [1 ]
Jin, Hye Jun [2 ]
Namgung, Seon [2 ]
Lee, Sang Hun [1 ]
Park, Tai Hyun [1 ]
Hong, Seunghun [2 ,3 ]
机构
[1] Seoul Natl Univ, Sch Chem & Biol Engn, BioMAX Inst, Seoul 151742, South Korea
[2] Seoul Natl Univ, Dept Phys & Astron, Seoul 151742, South Korea
[3] Seoul Natl Univ, Dept Biophys & Chem Biol, Seoul 151742, South Korea
基金
新加坡国家研究基金会;
关键词
UNSATURATED FATTY-ACIDS; OXIDATIVE DETERIORATION; SELECTIVE DETECTION; ODORANT; DEVICE; FLAVOR; MEAT;
D O I
10.1039/c2an16274a
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
We developed an olfactory-nanovesicle-fused carbon-nanotube-transistor biosensor (OCB) that mimics the responses of a canine nose for the sensitive and selective detection of hexanal, an indicator of the oxidation of food. OCBs allowed us to detect hexanal down to 1 fM concentration in real-time. Significantly, we demonstrated the detection of hexanal with an excellent selectivity capable of discriminating hexanal from analogous compounds such as pentanal, heptanal, and octanal. Furthermore, we successfully detected hexanal in spoiled milk without any pretreatment processes. Considering these results, our sensor platform should offer a new method for the assessment of food quality and contribute to the development of portable sensing devices.
引用
收藏
页码:3249 / 3254
页数:6
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