Microwave irradiation: A facile, scalable and convenient method for synthesis of N-phthaloylamino acids

被引：22
作者：
Al-Hazimi, Hassan M. [1 ]
El-Faham, Ayman [2 ]
Ghazzali, Mohamed [1 ]
Al-Farhan, Khalid [1 ]
机构：
[1] King Saud Univ, Coll Sci, Dept Chem, Riyadh 11451, Saudi Arabia
[2] Univ Alexandria, Fac Sci, Dept Chem, Alexandria 12321, Egypt
来源：
ARABIAN JOURNAL OF CHEMISTRY | 2012年 / 5卷 / 03期
关键词：
Phthalic anhydride; Phthalimide; Amino acid; N-protecting amino acid; Microwave irradiation; X-ray crystallography; COMPLEXES; DERIVATIVES; NETWORKS; DIIMIDE; ADDUCTS; MONO;
D O I：
10.1016/j.arabjc.2010.06.020
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We describe herein a fast and rapid technique for preparation of N-phthaloyl amino acids under microwave irradiation. The microwave methodology is rapid, convenient, proceeds under mild conditions, and gives a better yield (81-98%) and high purity of the title compounds. The spectral data as well as the X-ray analysis established the structure of the prepared N-protected amino acids. (C) 2012 King Saud University. Production and hosting by Elsevier B. V. All rights reserved.
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收藏
页码：285 / 289
页数：5
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