Microwave irradiation: A facile, scalable and convenient method for synthesis of N-phthaloylamino acids

被引：22

作者：

Al-Hazimi, Hassan M. ^{[1
]}

El-Faham, Ayman ^{[2
]}

Ghazzali, Mohamed ^{[1
]}

Al-Farhan, Khalid ^{[1
]}

机构：

[1] King Saud Univ, Coll Sci, Dept Chem, Riyadh 11451, Saudi Arabia

[2] Univ Alexandria, Fac Sci, Dept Chem, Alexandria 12321, Egypt

来源：

ARABIAN JOURNAL OF CHEMISTRY | 2012年 / 5卷 / 03期

关键词：

Phthalic anhydride; Phthalimide; Amino acid; N-protecting amino acid; Microwave irradiation; X-ray crystallography; COMPLEXES; DERIVATIVES; NETWORKS; DIIMIDE; ADDUCTS; MONO;

D O I：

10.1016/j.arabjc.2010.06.020

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We describe herein a fast and rapid technique for preparation of N-phthaloyl amino acids under microwave irradiation. The microwave methodology is rapid, convenient, proceeds under mild conditions, and gives a better yield (81-98%) and high purity of the title compounds. The spectral data as well as the X-ray analysis established the structure of the prepared N-protected amino acids. (C) 2012 King Saud University. Production and hosting by Elsevier B. V. All rights reserved.

引用

页码：285 / 289

页数：5

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