Microwave irradiation: A facile, scalable and convenient method for synthesis of N-phthaloylamino acids

被引：22

作者：

Al-Hazimi, Hassan M. ^{[1
]}

El-Faham, Ayman ^{[2
]}

Ghazzali, Mohamed ^{[1
]}

Al-Farhan, Khalid ^{[1
]}

机构：

[1] King Saud Univ, Coll Sci, Dept Chem, Riyadh 11451, Saudi Arabia

[2] Univ Alexandria, Fac Sci, Dept Chem, Alexandria 12321, Egypt

来源：

ARABIAN JOURNAL OF CHEMISTRY | 2012年 / 5卷 / 03期

关键词：

Phthalic anhydride; Phthalimide; Amino acid; N-protecting amino acid; Microwave irradiation; X-ray crystallography; COMPLEXES; DERIVATIVES; NETWORKS; DIIMIDE; ADDUCTS; MONO;

D O I：

10.1016/j.arabjc.2010.06.020

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We describe herein a fast and rapid technique for preparation of N-phthaloyl amino acids under microwave irradiation. The microwave methodology is rapid, convenient, proceeds under mild conditions, and gives a better yield (81-98%) and high purity of the title compounds. The spectral data as well as the X-ray analysis established the structure of the prepared N-protected amino acids. (C) 2012 King Saud University. Production and hosting by Elsevier B. V. All rights reserved.

引用

页码：285 / 289

页数：5

共 40 条

[1] N-Phthaloylglycinate ternary complexes with cobalt(II), nickel(II), copper(II), zinc(II) and cadmium(II) metal ions and aromatic mono, bi and tridentate amines
Abdel-Rahman, LH
[J]. TRANSITION METAL CHEMISTRY, 2001, 26 (4-5) : 412 - 416
[2] Self-assembly of supramolecular light-harvesting arrays from covalent multi-chromophore peryiene-3,4:9,10-bis(dicarboximide) building blocks
Ahrens, MJ
Sinks, LE
Rybtchinski, B
Liu, WH
Jones, BA
Giaimo, JM
Gusev, AV
Goshe, AJ
Tiede, DM
Wasielewski, MR
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (26) : 8284 - 8294
[3] [Anonymous], 1997, SHELXTL REF MAN VERS
[4] Adducts of 2-hydroxyethylphthalimide with 1,3-dihydroxybenene and 1,3,5-trihydroxybenzene
Barooah, N
Sarma, RJ
Baruah, JB
[J]. CRYSTAL GROWTH & DESIGN, 2003, 3 (05) : 639 - 641
[5] Self-assembly through hydrogen-bonding and C-H•••π interactions in metal complexes of N-functionalised glycine
Barooah, Nilotpal
Karmakar, Anirban
Sarma, Rupam J.
Baruah, Jubaraj B.
[J]. INORGANIC CHEMISTRY COMMUNICATIONS, 2006, 9 (12) : 1251 - 1254
[6] Structural aspects of adducts of N-phthaloylglycine and its derivatives
Barooah, Nilotpal
Sarma, Rupam J.
Batsanov, Andrei S.
Baruah, Jubaraj B.
[J]. JOURNAL OF MOLECULAR STRUCTURE, 2006, 791 (1-3) : 122 - 130
[7] Photophysical characterization of a 1,4,5,8-naphthalenediimide derivative
Barros, TC
Brochsztain, S
Toscano, VG
Berci, P
Politi, MJ
[J]. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 1997, 111 (1-3) : 97 - 104
[8] Bedair Ahmed H., 2006, Acta Pharmaceutica (Zagreb), V56, P273
[9] A general procedure of the peptide synthesis.
Bergmann, M
Zervas, L
[J]. BERICHTE DER DEUTSCHEN CHEMISCHEN GESELLSCHAFT, 1932, 65 (07): : 1192 - 1201
[10] BOSE AK, 1990, HETEROCYCLES, V30, P741

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