Optimal control applied to community-acquired methicillin-resistant Staphylococcus aureus in hospitals

被引：10

作者：

Ding, Wandi ^{[1
]}

Webb, Glenn F. ^{[2
]}

机构：

[1] Middle Tennessee State Univ, Dept Math Sci, Murfreesboro, TN 37130 USA

[2] Vanderbilt Univ, Dept Math, Nashville, TN 37235 USA

来源：

JOURNAL OF BIOLOGICAL DYNAMICS | 2017年 / 11卷 / 01期

关键词：

Optimal control; MRSA; decolonization; screening;

D O I：

10.1080/17513758.2016.1151564

中图分类号：

Q14 [生态学（生物生态学）];

学科分类号：

071012 ; 0713 ;

摘要：

Optimal control methods are applied to a deterministic mathematical model to characterize the factors contributing to the replacement of hospital-acquired methicillin-resistant Staphylococcus aureus (HA-MRSA) with community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA), and quantify the effectiveness of three interventions aimed at limiting the spread of CA-MRSA in healthcare settings. Characterizations of the optimal control strategies are established, and numerical simulations are provided to illustrate the results.

引用

页码：65 / 78

页数：14

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