The Effect of Pimelic Acid Interaction on the Mechanical and Thermal Properties of Chitosan and Collagen

被引:23
作者
Mitra, Tapas [1 ]
Sailakshmi, G. [1 ]
Gnanamani, A. [1 ]
Mandal, A. B. [1 ]
机构
[1] CSIR CLRI, Div Microbiol, Madras, Tamil Nadu, India
关键词
Biocompatibility; biopolymer; chitosan; mechanical property; scaffold; thermal property; CROSS-LINKING; FILMS; CYTOTOXICITY; BIOCOMPATIBILITY; POLYMER; TISSUES;
D O I
10.1080/00914037.2013.769161
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
An attempt was made on to evaluate the feasibility on interaction of pimelic acid with natural polymers, namely chitosan and collagen, and further assess the functional, mechanical, thermal and biocompatible properties. Pimelic acid cross-linked 3D-scaffold biopolymer of chitosan and collagen displayed appreciable mechanical strength, thermal stability, and biocompatibility. The chemistry of interaction suggested noncovalent interactions play a major role in deciding the property of the said materials and its suitability for biomedical applications.
引用
收藏
页码:572 / 582
页数:11
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