Respiratory Health Benefits and Risks of Living at Moderate Altitude

被引:18
作者
Grissom, Colin K. [1 ,2 ]
Jones, Barbara E. [2 ,3 ]
机构
[1] Intermt Med Ctr, Pulm & Crit Care Med, Murray, UT USA
[2] Univ Utah, Pulm & Crit Care Med, Salt Lake City, UT USA
[3] Salt Lake City Vet Affairs Hlth Syst, Pulm & Crit Care Med, Salt Lake City, UT USA
关键词
asthma; chronic obstructive pulmonary disease; high altitude; pulmonary hypertension; obstructive sleep apnea; OBSTRUCTIVE SLEEP-APNEA; EXERCISE-INDUCED BRONCHOCONSTRICTION; PULMONARY-HYPERTENSION; ALLERGEN AVOIDANCE; SIMULATED ALTITUDE; MOUNTAIN-SICKNESS; LUNG-DISEASES; HYPOXIA; ASTHMA; THERAPY;
D O I
10.1089/ham.2016.0142
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Grissom, Colin K., Barbara E. Jones. Respiratory health benefits and risks of living at moderate altitude. High Alt Med Biol 00:000-000, 2017.The respiratory system plays a critical role in the series of physiologic responses that occur at high altitude and allows individuals to adapt to and tolerate hypobaric hypoxia. Persons with underlying lung disease may have complications, but sometimes derive benefits, related to residence at high altitude. This review will focus on health benefits and risks of patients with underlying asthma, chronic obstructive pulmonary disease, pulmonary hypertension, or obstructive sleep apnea, who live at altitudes of 1500 to 4500m. We will also discuss maladaptive responses of the respiratory system at high altitude in previously healthy persons, including development of pulmonary hypertension and sleep-disordered breathing.
引用
收藏
页码:109 / 115
页数:7
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