Association of Frailty With Recovery From Disability Among Community-Dwelling Older Adults: Results From Two Large US Cohorts

被引:20
作者
Wu, Chenkai [1 ,2 ]
Kim, Dae H. [3 ,4 ]
Xue, Qian-Li [5 ,6 ]
Lee, David S. H. [7 ]
Varadhan, Ravi [6 ,8 ]
Odden, Michelle C. [2 ]
机构
[1] New York Med Coll, Dept Publ Hlth, Sch Hlth Sci & Practice, Valhalla, NY 10595 USA
[2] Oregon State Univ, Sch Biol & Populat Hlth Sci, Corvallis, OR 97331 USA
[3] Brigham & Womens Hosp, Dept Med, Div Pharmacoepidemiol & Pharmacoecon, 75 Francis St, Boston, MA 02115 USA
[4] Beth Israel Deaconess Med Ctr, Dept Med, Div Gerontol, Boston, MA 02215 USA
[5] Johns Hopkins Univ, Sch Med, Dept Med, Div Geriatr Med & Gerontol, Baltimore, MD 21205 USA
[6] Johns Hopkins Med Inst, Ctr Aging & Hlth, Baltimore, MD 21205 USA
[7] Oregon Hlth & Sci Univ, Oregon State Univ, Coll Pharm, Portland, OR 97201 USA
[8] Johns Hopkins Univ, Dept Oncol, Sidney Kimmel Comprehens Care Ctr, Div Biostat & Bioinformat, Baltimore, MD USA
来源
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES | 2019年 / 74卷 / 04期
关键词
Disablement process; Frailty; Resilience; Recovery; FUNCTIONAL DECLINE; RECENT TRENDS; MORTALITY; PEOPLE; HEALTH; INTERVENTION; TRAJECTORIES; AMERICANS; OUTCOMES; RISK;
D O I
10.1093/gerona/gly080
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Disability in activities of daily living (ADLs) is a dynamic process and transitions among different disability states are common. However, little is known about factors affecting recovery from disability. We examined the association between frailty and recovery from disability among nondisabled community-dwelling elders. We studied 1,023 adults from the Cardiovascular Health Study (CHS) and 685 adults from the Health and Retirement Study (HRS), who were 65 years and had incident disability, defined as having difficulty in 1 ADL (dressing, eating, toileting, bathing, transferring, walking across a room). Disability recovery was defined as having no difficulty in any ADLs. Frailty was assessed by slowness, weakness, exhaustion, inactivity, and shrinking. Persons were classified as nonfrail (0 criteria), prefrail (12 criteria), or frail (35 criteria). In total, 539 (52.7%) CHS participants recovered from disability within 1 year. Almost two-thirds of nonfrail persons recovered, while less than two-fifths of the frail recovered. In the HRS, 234 (34.2%) participants recovered from disability within 2 years. Approximately half of the nonfrail recovered, while less than one-fifth of the frail recovered. After adjustment, prefrail and frail CHS participants were 16% and 36% less likely to recover than the nonfrail, respectively. In the HRS, frail persons had a 41% lower likelihood of recovery than the nonfrail. Frailty is an independent predictor of poor recovery from disability among nondisabled older adults. These findings validate frailty as a marker of decreased resilience and may offer opportunities for individualized interventions and geriatric care based on frailty assessment.
引用
收藏
页码:575 / 581
页数:7
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