Pathology Consultation on Human Chorionic Gonadotropin Testing for Pregnancy Assessment

被引：10
作者：
Greene, Dina N. [1 ]
Grenache, David G. [2 ]
机构：
[1] Univ Washington, Dept Lab Med, Seattle, WA 98195 USA
[2] Univ Utah, Sch Med, Dept Pathol, Salt Lake City, UT USA
来源：
AMERICAN JOURNAL OF CLINICAL PATHOLOGY | 2015年 / 144卷 / 06期
关键词：
Clinical chemistry; Reproductive biochemistry; Pregnancy; hCG; POINT-OF-CARE; BETA-CORE FRAGMENT; REFERENCE REAGENTS; HCG DEVICES; ECTOPIC PREGNANCY; QUALITATIVE POINT; DOWN-SYNDROME; URINE; PERFORMANCE; WOMEN;
D O I：
10.1309/AJCP7O7VAREDUYIJ
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Objectives: To provide clarity on the use of qualitative and quantitative human chorionic gonadotropin (hCG) tests for the assessment of pregnancy. Methods: A case scenario and a brief review of the relevant literature describing clinical and analytical considerations regarding hCG testing are presented. Results: In pregnancy, hCG is nearly always detectable in serum and urine within 16 days after ovulation. Serial hCG testing is valuable in the evaluation of suspected ectopic pregnancy. hCG assays vary in their analytical specificity, and qualitative tests may be less analytically sensitive than claimed. Erroneous hCG test results can occur for several reasons. Conclusions: hCG assays are reliable diagnostic tests for pregnancy assessment, but a clear understanding of their limitations is necessary for appropriate result interpretation.
引用
收藏
页码：830 / 836
页数：7
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