Aptamer degradation inhibition combined with DNAzyme cascade-based signal amplification for colorimetric detection of proteins

被引：27

作者：

Li, Jishan ^{[1
]}

Jia, Yuhua ^{[1
]}

Zheng, Jing ^{[1
]}

Zhong, Wenwan ^{[2
]}

Shen, Guoli ^{[1
]}

Yang, Ronghua ^{[1
]}

Tan, Weihong ^{[1
]}

机构：

[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China

[2] Univ Calif Riverside, Dept Chem, Riverside, CA 92521 USA

来源：

CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 55期

基金：

美国国家科学基金会;

关键词：

IN-VITRO SELECTION; PEROXIDASE-ACTIVITY; CATALYTIC DNA; COMPLEX; THROMBIN; ASSAY; BIOSENSOR; LIGANDS; ENZYME; SENSOR;

D O I：

10.1039/c3cc42148a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Combining the inhibition of aptamer degradation with DNA Enzyme (DNAzyme) cascade-based signal amplification, a label-free and sensitive colorimetric protein assay strategy was proposed.

引用

页码：6137 / 6139

页数：3

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