Staphylococcus aureus subsp. anaerobius strain ST1464 genome sequence

被引：0

作者：

Elbir, Haitham ^{[1
]}

Robert, Catherine ^{[1
]}

Nguyen, Ti Thien ^{[1
]}

Gimenez, Gregory ^{[1
]}

El Sanousi, Sulieman M. ^{[2
]}

Flock, Jan-Ingmar ^{[3
]}

Raoult, Didier ^{[1
]}

Drancourt, Michel ^{[1
]}

机构：

[1] Aix Marseille Univ, URMITE, Marseille, France

[2] Univ Khartoum, Fac Vet Med, Khartoum, Sudan

[3] Dept Microbiol Tumor & Cell Biol, Stockholm, Sweden

来源：

STANDARDS IN GENOMIC SCIENCES | 2013年 / 9卷 / 01期

关键词：

Staphylococcus aureus subsp anaerobius; genome; SOLiD; Morel's disease; ABSCESS DISEASE; BACTERIA; DATABASE; SHEEP; TOOL;

D O I：

10.4056/sigs.3747423

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Staphylococcus aureus subsp. anaerobius is responsible for Morel's disease in animals and a cause of abscess in humans. It is characterized by a microaerophilic growth, contrary to the other strains of S. aureus. The 2,604,446-bp genome (32.7% GC content) of S. anaerobius ST1464 comprises one chromosome and no plasmids. The chromosome contains 2,660 open reading frames (ORFs), 49 tRNAs and three complete rRNAs, forming one complete operon. The size of ORFs ranges between 100 to 4,600 bp except for two ORFs of 6,417 and 7,173 bp encoding segregation ATPase and non-ribosomal peptide synthase, respectively. The chromosome harbors Staphylococcus phage 2638A genome and incomplete Staphylococcus phage genome PT1028, but no detectable CRISPRS. The antibiotic resistance gene for tetracycline was found although Staphylococcus aureus subsp. anaerobius is susceptible to tetracycline in-vitro. Intact oxygen detoxification genes encode superoxide dismutase and cytochrome quinol oxidase whereas the catalase gene is impaired by a stop codon. Based on the genome, in-silico multilocus sequence typing indicates that S. aureus subsp. anaerobius emerged as a clone separated from all other S. aureus strains, illustrating host-adaptation linked to missing functions. Availability of S. aureus subsp. anaerobius genome could prompt the development of post-genomic tools for its rapid discrimination from S. aureus.

引用

页码：1 / 13

页数：13

共 37 条

[11]

Euzeby J., 2010, INT J SYST EVOL MICR, V60, P469

[12] The minimum information about a genome sequence (MIGS) specification [J].

Field, Dawn ;

Garrity, George ;

Gray, Tanya ;

Morrison, Norman ;

Selengut, Jeremy ;

Sterk, Peter ;

Tatusova, Tatiana ;

Thomson, Nicholas ;

Allen, Michael J. ;

Angiuoli, Samuel V. ;

Ashburner, Michael ;

Axelrod, Nelson ;

Baldauf, Sandra ;

Ballard, Stuart ;

Boore, Jeffrey ;

Cochrane, Guy ;

Cole, James ;

Dawyndt, Peter ;

De Vos, Paul ;

dePamphilis, Claude ;

Edwards, Robert ;

Faruque, Nadeem ;

Feldman, Robert ;

Gilbert, Jack ;

Gilna, Paul ;

Gloeckner, Frank Oliver ;

Goldstein, Philip ;

Guralnick, Robert ;

Haft, Dan ;

Hancock, David ;

Hermjakob, Henning ;

Hertz-Fowler, Christiane ;

Hugenholtz, Phil ;

Joint, Ian ;

Kagan, Leonid ;

Kane, Matthew ;

Kennedy, Jessie ;

Kowalchuk, George ;

Kottmann, Renzo ;

Kolker, Eugene ;

Kravitz, Saul ;

Kyrpides, Nikos ;

Leebens-Mack, Jim ;

Lewis, Suzanna E. ;

Li, Kelvin ;

Lister, Allyson L. ;

Lord, Phillip ;

Maltsev, Natalia ;

Markowitz, Victor ;

Martiny, Jennifer .

NATURE BIOTECHNOLOGY, 2008, 26 (05) :541-547

[13]

Garrity G.M., 2001, BERGEYS MAN SYST BAC, V2nd, P119, DOI [10.1007/978-0-387-21609-6_15, DOI 10.1007/978-0-387-21609-6_15]

[14] PROPOSALS CONCERNING HIGHER TAXA OF BACTERIA [J].

GIBBONS, NE ;

MURRAY, RGE .

INTERNATIONAL JOURNAL OF SYSTEMATIC BACTERIOLOGY, 1978, 28 (01) :1-6

[15] Prodigal: prokaryotic gene recognition and translation initiation site identification [J].

Hyatt, Doug ;

Chen, Gwo-Liang ;

LoCascio, Philip F. ;

Land, Miriam L. ;

Larimer, Frank W. ;

Hauser, Loren J. .

BMC BIOINFORMATICS, 2010, 11

[16] Predicting transmembrane protein topology with a hidden Markov model: Application to complete genomes [J].

Krogh, A ;

Larsson, B ;

von Heijne, G ;

Sonnhammer, ELL .

JOURNAL OF MOLECULAR BIOLOGY, 2001, 305 (03) :567-580

[17] The complete genomes and proteomes of 27 Staphylococcus aureus bacteriophages [J].

Kwan, T ;

Liu, J ;

DuBow, M ;

Gros, P ;

Pelletier, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (14) :5174-5179

[18] ARAGORN, a program to detect tRNA genes and tmRNA genes in nucleotide sequences [J].

Laslett, D ;

Canback, B .

NUCLEIC ACIDS RESEARCH, 2004, 32 (01) :11-16

[19] Adaptation of Porphyromonas gingivalis to microaerophilic conditions involves increased consumption of formate and reduced utilization of lactate [J].

Lewis, Janina P. ;

Iyer, Divya ;

Anaya-Bergman, Cecilia .

MICROBIOLOGY-SGM, 2009, 155 :3758-3774

[20]

Ludwig W., 2009, Bergey's Manual of Systematic Bacteriology, V3, P19

← 1 2 3 4 →