Pauson-Khand Reactions in a Photochemical Flow Microreactor

被引：50
作者：
Asano, Keisuke [1 ]
Uesugi, Yuki [1 ]
Yoshida, Jun-ichi [1 ]
机构：
[1] Kyoto Univ, Dept Synthet Chem & Biol Chem, Grad Sch Engn, Nishikyo Ku, Kyoto 6158510, Japan
来源：
ORGANIC LETTERS | 2013年 / 15卷 / 10期
关键词：
N-OXIDE; 2+2 PHOTOCYCLOADDITION; ALKYNE COMPLEXES; FLASH CHEMISTRY; CYCLOADDITION; CYCLIZATIONS; CONVENIENT; REGIOSELECTIVITY; DERIVATIVES; GENERATION;
D O I：
10.1021/ol4008519
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Pauson-Khand reactions were achieved at ambient temperature without any additive using a photochemical flow microreactor. The efficiency of the reaction was better than that in a conventional batch reactor, and the reaction could be operated continuously for 1 h.
引用
收藏
页码：2398 / 2401
页数：4
相关论文
共 105 条
  • [1] Albini A., 2009, HDB SYNTHETIC PHOTOC
  • [2] Development of an Improved Process for Doxercalciferol via a Continuous Photochemical Reaction
    Anderson, Bruce G.
    Bauta, William E.
    Cantrell, William R., Jr.
    [J]. ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2012, 16 (05) : 967 - 975
  • [3] [Anonymous], 2003, CRC HDB ORGANIC PHOT
  • [4] [Anonymous], TRANSITION METALS OR
  • [5] THE EFFECT OF ULTRASOUND AND OF PHOSPHINE AND PHOSPHINE-OXIDES ON THE KHAND REACTION
    BILLINGTON, DC
    HELPS, IM
    PAUSON, PL
    THOMSON, W
    WILLISON, D
    [J]. JOURNAL OF ORGANOMETALLIC CHEMISTRY, 1988, 354 (02) : 233 - 242
  • [6] The Pauson-Khand reaction, a powerful synthetic tool for the synthesis of complex molecules
    Blanco-Urgoiti, J
    Añorbe, L
    Pérez-Serrano, L
    Domínguez, G
    Pérez-Castells, J
    [J]. CHEMICAL SOCIETY REVIEWS, 2004, 33 (01) : 32 - 42
  • [7] When the Pauson-Khand and Pauson-Khand type reactions go awry:: a plethora of unexpected results
    Boñaga, LVR
    Krafft, ME
    [J]. TETRAHEDRON, 2004, 60 (44) : 9795 - 9833
  • [8] THE SYNTHESIS OF NITROGEN-HETEROCYCLES VIA THE INTRAMOLECULAR KHAND REACTION - FORMATION OF TETRA-HYDROCYCLOPENTA[C]PYRROL-5(1H)-ONES AND HEXA-HYDROCYCLOPENTA[C]PYRROL-5(1H)-ONES AND HEXAHYDRO-6H-2-PYRINDIN-6-ONES
    BROWN, SW
    PAUSON, PL
    [J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1990, (04): : 1205 - 1209
  • [9] Recent advances in the Pauson-Khand reaction and related [2+2+1] cycloadditions
    Brummond, KM
    Kent, JL
    [J]. TETRAHEDRON, 2000, 56 (21) : 3263 - 3283
  • [10] BUCHWALD SL, 2000, COMPREHENSIVE ASYMME, V2, P491
12345678910