A Three-Station DNA Catenane Rotary Motor with Controlled Directionality

被引：87
作者：
Lu, Chun-Hua [1 ,2 ]
Cecconello, Alessandro [1 ,2 ]
Elbaz, Johann [1 ,2 ]
Credi, Alberto [3 ]
Willner, Itamar [1 ,2 ]
机构：
[1] Hebrew Univ Jerusalem, Inst Chem, IL-91904 Jerusalem, Israel
[2] Hebrew Univ Jerusalem, Minerva Ctr Biohybrid Complex Syst, IL-91904 Jerusalem, Israel
[3] Univ Bologna, Dipartimento Chim G Ciamician, Photochem Nanosci Lab, I-40126 Bologna, Italy
来源：
NANO LETTERS | 2013年 / 13卷 / 05期
基金：
以色列科学基金会;
关键词：
DNA; machine; catenane; nanotechnology; fluorescence resonance energy transfer (FRET); RELEASE;
D O I：
10.1021/nl401010e
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The assembly of DNA machines represents a central effort in DNA nanotechnology. We report on the first DNA rotor system composed of a two-ring catenane. The DNA rotor ring rotates in dictated directions along a wheel, and it occupies three distinct sites. Hg2+/cysteine or pH (H+/OH-) act as fuels or antifuels in positioning the rotor ring. Analysis of the kinetics reveals directional clockwise or anticlockwise population of the target-sites (>85%), and the rotor's direction is controlled by the shortest path on the wheel.
引用
收藏
页码：2303 / 2308
页数：6
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