Stabilization of protein structures

被引：53

作者：

Lee, B

Vasmatzis, G

机构：

[1] Div. of Cancer Biology, Diagnosis, Centers National Cancer Institute, Natl. Institutes of Hlth. Bldg. 37, 37 Convent DR MSC 4255, Bethesda

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 1997年 / 8卷 / 04期

关键词：

D O I：

10.1016/S0958-1669(97)80063-8

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The technique of protein stabilization has been improving steadily in recent years, but it is only in the past year or two that the stability of some protein molecules has been improved to the level of those from extreme thermophilic organisms, This was achieved by multiple mutations and often by utilizing the knowledge gained from the homologous protein structures from extreme thermophiles.

引用

页码：423 / 428

页数：6

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