EFFICIENT SYNTHESIS OF α,β-DIAMINO ACID DERIVATIVES BY In(III)-CATALYZED REGIOSELECTIVE ADDITION OF AMINES TO AZIRIDINES

被引：1

作者：

Hu, Xiao-Yu ^{[1
,2
]}

Yang, Xiang-Yu ^{[1
,2
]}

Cheng, Ming ^{[1
,2
]}

Zhang, Qiang ^{[1
,2
]}

Wei, Wei ^{[1
,2
]}

Ji, Jian-Xin ^{[1
]}

机构：

[1] Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Peoples R China

[2] Chinese Acad Sci, Grad Univ, Beijing, Peoples R China

来源：

SYNTHETIC COMMUNICATIONS | 2012年 / 42卷 / 23期

基金：

美国国家科学基金会;

关键词：

Amines; aziridines; catalytic synthesis; alpha; beta-diamino acid; indium(III) salt; RING-OPENING REACTIONS; OPTICALLY-ACTIVE N-ACETYL-2-METHOXYCARBONYLAZIRIDINE; ASYMMETRIC-SYNTHESIS; BETA-LACTAMS; IMINE CONDENSATION; N-TOSYLAZIRIDINES; ESTER ENOLATE; ALPHA; DIAMINES;

D O I：

10.1080/00397911.2011.582977

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient catalytic method for the synthesis of alpha,beta-diamino acid derivatives has been developed via regioselective ring opening of aziridines by amines in the presence of indium( III) salt under very mild reaction conditions. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications(R) to view the free supplemental file.

引用

页码：3403 / 3412

页数：10

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