ECHINOCANDIN AND ETHANOL LOCK THERAPY TREATMENT OF FUNGAL CATHETER INFECTIONS

被引:14
作者
Pieroni, Kevin P. [1 ]
Nespor, Colleen [2 ]
Poole, Robert L. [2 ,3 ]
Kerner, John A., Jr. [1 ,2 ]
Berquist, William E. [1 ]
机构
[1] Stanford Univ, Sch Med, Div Gastroenterol Hepatol & Nutr, Dept Pediat, Palo Alto, CA 94304 USA
[2] Childrens Home Pharm, Palo Alto, CA USA
[3] Lucile Packard Childrens Hosp Stanford, Dept Pharm, Palo Alto, CA 94304 USA
关键词
ethanol locks; catheter infection; fungal infections; BLOOD-STREAM INFECTIONS; PARENTERAL-NUTRITION PATIENTS; CANDIDA-ALBICANS BIOFILMS; INTESTINAL FAILURE; PEDIATRIC-PATIENTS; ANTIFUNGAL AGENTS; EFFICACY; REDUCE;
D O I
10.1097/INF.0b013e3182784867
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Ethanol lock therapy has been implemented to prevent infections of central venous catheters as well as to treat infections. Fungal catheter-associated blood stream infections are historically more difficult to treat and have required removal of central venous catheters. We report the largest case series to date, successfully treating 5 of 7 fungal catheter-associated blood stream infections with ethanol lock therapy and systemic echinocandin administration.
引用
收藏
页码:289 / 291
页数:3
相关论文
共 50 条
  • [41] Preliminary results of a phase I trial of prophylactic ethanol-lock administration to prevent mediport catheter-related bloodstream infections
    Kayton, Mark L.
    Garmey, Edward G.
    Ishill, Nicole M.
    Cheung, Nai-Kong V.
    Kushner, Brian H.
    Kramer, Kim
    Modak, Shakeel
    Rossetto, Carol
    Hennelly, Courtney
    Doyle, Melissa Parra
    Rosenberg, Shoshana
    Santoro, Olga
    La Quaglia, Michael P.
    JOURNAL OF PEDIATRIC SURGERY, 2010, 45 (10) : 1961 - 1966
  • [42] Pathogenesis and treatment of fungal infections by Candida spp.
    Staniszewska, Monika
    Bondaryk, Malgorzata
    Kowalska, Marzena
    Magda, Urszula
    Luka, Martyna
    Ochal, Zbigniew
    Kurzatkowski, Wieslaw
    POSTEPY MIKROBIOLOGII, 2014, 53 (03): : 229 - 240
  • [43] Taurolidine lock: The key to prevention of recurrent catheter-related bloodstream infections
    Jurewitsch, B
    Jeejeebhoy, KN
    CLINICAL NUTRITION, 2005, 24 (03) : 462 - 465
  • [44] Treatment of long-term intravascular catheter-related bacteraemia with antibiotic-lock therapy
    Fortun, J.
    Grill, F.
    Martin-Davila, P.
    Blazquez, J.
    Tato, M.
    Sanchez-Corral, J.
    Miguel, L. Garcia-San
    Moreno, S.
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2006, 58 (04) : 816 - 821
  • [45] In Vitro and In Vivo Activity of a Novel Catheter Lock Solution against Bacterial and Fungal Biofilms
    Chandra, J.
    Long, L.
    Isham, N.
    Mukherjee, P. K.
    DiSciullo, G.
    Appelt, K.
    Ghannoum, M. A.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2018, 62 (08)
  • [46] Adoptive T-cell therapy in the treatment of viral and opportunistic fungal infections
    Mancini, Nicasio
    Marrone, Lara
    Clementi, Nicola
    Sautto, Giuseppe A.
    Clementi, Massimo
    Burioni, Roberto
    FUTURE MICROBIOLOGY, 2015, 10 (04) : 665 - 682
  • [47] Use of 2% taurolidine lock solution for treatment and prevention of catheter-related bloodstream infections in neonates: a feasibility study
    Savarese, I.
    Yazami, S.
    De Rose, D. U.
    Carkeek, K.
    Campi, F.
    Auriti, C.
    Danhaive, O.
    Piersigilli, F.
    JOURNAL OF HOSPITAL INFECTION, 2024, 143 : 76 - 81
  • [48] Evaluation of Ethanol Lock Therapy in Pediatric Patients on Long-Term Parenteral Nutrition
    Pieroni, Kevin P.
    Nespor, Colleen
    Ng, Marisa
    Garcia, Manuel
    Hurwitz, Melissa
    Berquist, William E.
    Kerner, John A., Jr.
    NUTRITION IN CLINICAL PRACTICE, 2013, 28 (02) : 226 - 231
  • [49] Comparative Efficacies of Antimicrobial Catheter Lock Solutions for Fungal Biofilm Eradication in an in Vitro Model of Catheter-Related Fungemia
    Rosenblatt, Joel
    Reitzel, Ruth A.
    Vargas-Cruz, Nylev
    Chaftari, Anne-Marie
    Hachem, Ray
    Raad, Issam I.
    JOURNAL OF FUNGI, 2017, 3 (01)
  • [50] Ethanol lock therapy in pediatric patients: A multicenter prospective study
    Chiba, Masahiro
    Yonekura, Takeo
    Kaji, Tatsuru
    Amae, Shintaro
    Tazuke, Yuko
    Oowari, Mitsugu
    Obana, Kazuko
    Nakano, Miwako
    Kuroda, Tasuo
    Fukumoto, Kouzi
    Yamane, Yusuke
    Yoshino, Hiroaki
    Hebiguchi, Tatsuzo
    Toki, Akira
    PEDIATRICS INTERNATIONAL, 2020, 62 (03) : 379 - 385