ECHINOCANDIN AND ETHANOL LOCK THERAPY TREATMENT OF FUNGAL CATHETER INFECTIONS

被引:14
作者
Pieroni, Kevin P. [1 ]
Nespor, Colleen [2 ]
Poole, Robert L. [2 ,3 ]
Kerner, John A., Jr. [1 ,2 ]
Berquist, William E. [1 ]
机构
[1] Stanford Univ, Sch Med, Div Gastroenterol Hepatol & Nutr, Dept Pediat, Palo Alto, CA 94304 USA
[2] Childrens Home Pharm, Palo Alto, CA USA
[3] Lucile Packard Childrens Hosp Stanford, Dept Pharm, Palo Alto, CA 94304 USA
关键词
ethanol locks; catheter infection; fungal infections; BLOOD-STREAM INFECTIONS; PARENTERAL-NUTRITION PATIENTS; CANDIDA-ALBICANS BIOFILMS; INTESTINAL FAILURE; PEDIATRIC-PATIENTS; ANTIFUNGAL AGENTS; EFFICACY; REDUCE;
D O I
10.1097/INF.0b013e3182784867
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Ethanol lock therapy has been implemented to prevent infections of central venous catheters as well as to treat infections. Fungal catheter-associated blood stream infections are historically more difficult to treat and have required removal of central venous catheters. We report the largest case series to date, successfully treating 5 of 7 fungal catheter-associated blood stream infections with ethanol lock therapy and systemic echinocandin administration.
引用
收藏
页码:289 / 291
页数:3
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