MR-Guided High-Intensity Focused Ultrasound: Current Status of an Emerging Technology

被引：110

作者：

Napoli, Alessandro ^{[1
]}

Anzidei, Michele ^{[1
]}

Ciolina, Federica ^{[1
]}

Marotta, Eugenio ^{[1
]}

Marincola, Beatrice Cavallo ^{[1
]}

Brachetti, Giulia ^{[1
]}

Di Mare, Luisa ^{[1
]}

Cartocci, Gaia ^{[1
]}

Boni, Fabrizio ^{[1
]}

Noce, Vincenzo ^{[1
]}

Bertaccini, Luca ^{[1
]}

Catalano, Carlo ^{[1
]}

机构：

[1] Univ Rome, Dept Radiol Sci, I-00161 Rome, Italy

来源：

CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY | 2013年 / 36卷 / 05期

关键词：

Ablation; Cancer; High intensity focused ultrasound; MR-guided intervention; Noninvasive treatment; BLOOD-BRAIN-BARRIER; ADVANCED PANCREATIC-CANCER; UTERINE FIBROIDS; BONE METASTASES; HEPATOCELLULAR-CARCINOMA; CLINICAL-OUTCOMES; PROSTATE-CANCER; SURGERY MRGFUS; BREAST-CANCER; SAFE THERAPY;

D O I：

10.1007/s00270-013-0592-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The concept of ideal tumor surgery is to remove the neoplastic tissue without damaging adjacent normal structures. High-intensity focused ultrasound (HIFU) was developed in the 1940s as a viable thermal tissue ablation approach. In clinical practice, HIFU has been applied to treat a variety of solid benign and malignant lesions, including pancreas, liver, prostate, and breast carcinomas, soft tissue sarcomas, and uterine fibroids. More recently, magnetic resonance guidance has been applied for treatment monitoring during focused ultrasound procedures (magnetic resonance-guided focused ultrasound, MRgFUS). Intraoperative magnetic resonance imaging provides the best possible tumor extension and dynamic control of energy deposition using real-time magnetic resonance imaging thermometry. We introduce the fundamental principles and clinical indications of the MRgFUS technique; we also report different treatment options and personal outcomes.

引用

页码：1190 / 1203

页数：14

共 59 条

[1] Focal therapy for localised unifocal and multifocal prostate cancer: a prospective development study [J].