Next-generation sequencing technologies, microarrays and advances in bio nanotechnology have had an enormous impact on research within a short time frame. This impact appears certain to increase further as many biomedical institutions are now acquiring these prevailing new technologies. Beyond conventional sampling of genome content, wide-ranging applications are rapidly evolving for next-generation sequencing, microarrays and nanotechnology. To date, these technologies have been applied in a variety of contexts, including whole-genome sequencing, targeted re sequencing and discovery of transcription factor binding sites, noncoding RNA expression profiling and molecular diagnostics. This paper thus discusses current applications of nanotechnology, next-generation sequencing technologies and microarrays in biomedical research and highlights the transforming potential these technologies offer.
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Christian Med Coll & Hosp, Dept Haematol, Vellore 632004, Tamil Nadu, IndiaChristian Med Coll & Hosp, Dept Haematol, Vellore 632004, Tamil Nadu, India
Maddali, Madhavi
Balasubramanian, Poonkuzhali
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Christian Med Coll & Hosp, Dept Haematol, Vellore 632004, Tamil Nadu, IndiaChristian Med Coll & Hosp, Dept Haematol, Vellore 632004, Tamil Nadu, India
机构:
Harvard Med Sch, Massachusetts Eye & Ear Infirm, David G Cogan Lab Ophthalm Pathol, Boston, MA 02115 USAHarvard Med Sch, Massachusetts Eye & Ear Infirm, David G Cogan Lab Ophthalm Pathol, Boston, MA 02115 USA
Ma, Lina
Jakobiec, Frederick A.
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Harvard Med Sch, Massachusetts Eye & Ear Infirm, David G Cogan Lab Ophthalm Pathol, Boston, MA 02115 USAHarvard Med Sch, Massachusetts Eye & Ear Infirm, David G Cogan Lab Ophthalm Pathol, Boston, MA 02115 USA
Jakobiec, Frederick A.
Dryja, Thaddeus P.
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Harvard Med Sch, Massachusetts Eye & Ear Infirm, David G Cogan Lab Ophthalm Pathol, Boston, MA 02115 USAHarvard Med Sch, Massachusetts Eye & Ear Infirm, David G Cogan Lab Ophthalm Pathol, Boston, MA 02115 USA
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Mem Sloan Kettering Canc Ctr, Dept Med, Gastrointestinal Oncol Serv, 1275 York Ave, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Dept Med, Gastrointestinal Oncol Serv, 1275 York Ave, New York, NY 10021 USA