Fabrication of a Modified Electrode Based on Fe3O4-Graphene Oxide Hybrid Composite: Applying to Simultaneous Determination of Adenine and Guanine in DNA

被引：10
作者：
Xie, Qianjie [2 ]
Chen, Xiang-yu [2 ]
Zhang, Hanzhi [2 ]
Liu, Mengdi [2 ]
Wang, Qian [3 ]
Zhang, Xin [1 ]
Shen, Yehua [2 ]
Yang, Fengchun [2 ]
机构：
[1] NW Univ Xian, Inst Analyt Sci, Shaanxi Prov Key Lab Electroanalyt Chem, Xian 710069, Shaanxi, Peoples R China
[2] NW Univ Xian, Coll Chem & Mat Sci, Key Lab Synthet & Nat Funct Mol Chem, Minist Educ, Xian 710069, Shaanxi, Peoples R China
[3] Xian Univ Posts & Telecommun, Sch Telecommun & Informat Engn, Xian 710121, Shaanxi, Peoples R China
来源：
ELECTROANALYSIS | 2015年 / 27卷 / 09期
关键词：
Fe3O4; nanoparticles; Graphene oxide; Adenine; Guanine; Simultaneous determination; DNA; GLASSY-CARBON ELECTRODE; ELECTROCHEMICAL SENSOR; MASS-SPECTROMETRY; ASCORBIC-ACID; URIC-ACID; GRAPHENE; NANOCOMPOSITE; NANOPARTICLES; FILM; OXIDATION;
D O I：
10.1002/elan.201500186
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A Fe3O4-graphene oxide hybrid composite (Fe3O4- GO) was synthesized and used to construct a novel electrochemical sensor for the simultaneous detection of adenine and guanine. The Fe3O4-GO based electrochemical sensor exhibits linear ranges of 0.05-25 mu M and 0.05-25 mu M with detection limits of 4 nM and 3 nM for adenine and guanine, respectively. This method was applied in the determination of guanine and adenine in many samples with satisfying results. The value of (G+C)/(A+T) in DNA was calculated to be 0.7536. The sensor exhibits some advantages, such as rapidity, good reproducibility and long-term stability.
引用
收藏
页码：2201 / 2208
页数：8
相关论文
共 50 条
  • [21] Poly(glycine)/graphene oxide modified glassy carbon electrode: Preparation, characterization and simultaneous electrochemical determination of dopamine, uric acid, guanine and adenine
    He, Shaoying
    He, Ping
    Zhang, Xingquan
    Zhang, Xiaojuan
    Liu, Kaili
    Jia, Lingpu
    Dong, Faqin
    ANALYTICA CHIMICA ACTA, 2018, 1031 : 75 - 82
  • [22] Electrochemical sensor for individual and simultaneous determination of guanine and adenine in biological fluids and in DNA based on a nano-In-ceria modified glassy carbon paste electrode
    Ibrahim, Hossieny
    Temerk, Yassien
    Farhan, Nasser
    RSC ADVANCES, 2016, 6 (93): : 90220 - 90231
  • [23] Electrochemical sensing and simultaneous determination of guanine and adenine based on covalent organic frameworks/NH2-rG/MoS2 modified glassy carbon electrode
    Zhao, Xin
    Guo, Hao
    Xue, Rui
    Wang, Mingyue
    Guan, Qixia
    Fan, Tian
    Yang, Wenhu
    Yang, Wu
    MICROCHEMICAL JOURNAL, 2021, 160
  • [24] Architecture of Fe3O4-graphene oxide nanocomposite and its application as a platform for amino acid biosensing
    Song, Yonghai
    He, Zhifang
    Hou, Haoqing
    Wang, Xiaolan
    Wang, Li
    ELECTROCHIMICA ACTA, 2012, 71 : 58 - 65
  • [25] Reduced graphene oxide-graphene quantum dots-Fe3O4 nanocomposite modified electrode for determination of dopamine
    Ershadian, Fatemeh
    Elhami, Shahla
    CHEMICAL PAPERS, 2023, 77 (11) : 6613 - 6627
  • [26] Fabrication of poly(2,6-pyridinedicarboxylic acid)/MWNTs modified electrode for simultaneous determination of guanine and adenine in DNA
    Ke Qin Deng~*
    Chinese Chemical Letters, 2011, 22 (08) : 981 - 984
  • [27] Fabrication of poly (2,6-pyridinedicarboxylic acid)/MWNTs modified electrode for simultaneous determination of guanine and adenine in DNA
    Deng, Ke Qin
    Li, Chun Xiang
    Ling, Yu Lin
    Xu, Guo Rong
    Li, Xiao Fang
    CHINESE CHEMICAL LETTERS, 2011, 22 (08) : 981 - 984
  • [28] Covalent organic framework derived Fe3O4/N co-doped hollow carbon nanospheres modified electrode for simultaneous determination of biomolecules in human serum
    Lu, Zhenyu
    Shi, Zhaoxia
    Huang, Simin
    Zhang, Runkun
    Li, Gongke
    Hu, Yufei
    TALANTA, 2020, 214
  • [29] Simultaneous and sensitive determination of melatonin and dopamine with Fe3O4 nanoparticle-decorated reduced graphene oxide modified electrode
    Bagheri, H.
    Afkhami, A.
    Hashemi, P.
    Ghanei, M.
    RSC ADVANCES, 2015, 5 (28): : 21659 - 21669
  • [30] Label-free electrochemical DNA biosensor for guanine and adenine by ds-DNA/poly(L-cysteine)/Fe3O4 nanoparticles-graphene oxide nanocomposite modified electrode
    Arvand, Majid
    Sanayeei, Mona
    Hemmati, Shiva
    BIOSENSORS & BIOELECTRONICS, 2018, 102 : 70 - 79
12345