Genomic dissection of microbial pathogenesis in cultured Drosophila cells

被引：10

作者：

Ayres, JS ^{[1
]}

Schneider, DS ^{[1
]}

机构：

[1] Stanford Univ, Dept Microbiol & Immunol, Stanford, CA 94305 USA

来源：

TRENDS IN MICROBIOLOGY | 2006年 / 14卷 / 03期

关键词：

D O I：

10.1016/j.tim.2006.01.008

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent RNA interference screens that were performed at a genome-wide level have identified host factors that are important for the growth of Listeria monocytogenes in cultured cells from the fruit fly Drosophila melanogaster. The screens identified genes that are involved in phagocytosis but did not detect genes known to be involved in immune signaling pathways. These studies provide a foundation for the identification of host factors and virulence mechanisms.

引用

页码：101 / 104

页数：4

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