Reactions of All Escherichia coli Lytic Transglycosylases with Bacterial Cell Wall

被引:80
作者
Lee, Mijoon [1 ]
Hesek, Dusan [1 ]
Llarrull, Leticia I. [1 ]
Lastochkin, Elena [1 ]
Pi, Hualiang [1 ]
Boggess, Bill [1 ]
Mobashery, Shahriar [1 ]
机构
[1] Univ Notre Dame, Dept Chem & Biochem, Notre Dame, IN 46556 USA
关键词
PSEUDOMONAS-AERUGINOSA; MUREIN HYDROLASES; PEPTIDOGLYCAN; ARCHITECTURE; ENZYMES;
D O I
10.1021/ja309036q
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The reactions of all seven Escherichia coli lytic transglycosylases with purified bacterial sacculus are characterized in a quantitative manner. These reactions, which initiate recycling of the bacterial cell wall, exhibit significant redundancy in the activities of these enzymes along with some complementarity. These discoveries underscore the importance of the functions of these enzymes for recycling of the cell wall.
引用
收藏
页码:3311 / 3314
页数:4
相关论文
共 27 条
[1]  
[Anonymous], THESIS RIJKSUNIVERSI
[2]   Detailed structural analysis of the peptidoglycan of the human pathogen Neisseria meningitidis [J].
Antignac, A ;
Rousselle, JC ;
Namane, A ;
Labigne, A ;
Taha, MK ;
Boneca, IG .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (34) :31521-31528
[3]   Synthesis of mosaic peptidoglycan cross-bridges by hybrid peptidoglycan assembly pathways in gram-positive bacteria [J].
Arbeloa, A ;
Hugonnet, JE ;
Sentilhes, AC ;
Josseaume, N ;
Dubost, L ;
Monsempes, C ;
Blanot, D ;
Brouard, JP ;
Arthur, M .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (40) :41546-41556
[4]   The Lytic Transglycosylases of Neisseria gonorrhoeae [J].
Chan, Yolande A. ;
Hackett, Kathleen T. ;
Dillard, Joseph P. .
MICROBIAL DRUG RESISTANCE, 2012, 18 (03) :271-279
[5]   Characterization of Helicobacter pylori lytic transglycosylases Slt and MltD [J].
Chaput, Catherine ;
Labigne, Agnes ;
Boneca, Ivo G. .
JOURNAL OF BACTERIOLOGY, 2007, 189 (02) :422-429
[6]   MUREIN-METABOLIZING ENZYMES FROM ESCHERICHIA-COLI - EXISTENCE OF A 2ND LYTIC TRANSGLYCOSYLASE [J].
ENGEL, H ;
SMINK, AJ ;
VANWIJNGAARDEN, L ;
KECK, W .
JOURNAL OF BACTERIOLOGY, 1992, 174 (20) :6394-6403
[7]  
GLAUNER B, 1988, J BIOL CHEM, V263, P10088
[8]   Contributions of Four Cortex Lytic Enzymes to Germination of Bacillus anthracis Spores [J].
Heffron, Jared D. ;
Lambert, Emily A. ;
Sherry, Nora ;
Popham, David L. .
JOURNAL OF BACTERIOLOGY, 2010, 192 (03) :763-770
[9]   Effects of multiple deletions of murein hydrolases on viability, septum cleavage, and sensitivity to large toxic molecules in Escherichia coli [J].
Heidrich, C ;
Ursinus, A ;
Berger, J ;
Schwarz, H ;
Höltje, JV .
JOURNAL OF BACTERIOLOGY, 2002, 184 (22) :6093-6099
[10]  
HOLTJE JV, 1975, J BACTERIOL, V124, P1067