Cytotoxic lignans of Justicia ciliata

被引：44
作者：
Day, SH
Chiu, NY
Won, SJ
Lin, CN [1 ]
机构：
[1] Kaohsiung Med Coll, Sch Pharm, Kaohsiung 807, Taiwan
[2] Ta Jen Pharmaceut Jr Coll, Ping Tung Hsieng 907, Taiwan
[3] China Med Coll, Inst Chinese Pharmaceut Sci, Taichung 404, Taiwan
[4] Natl Cheng Kung Univ, Dept Microbiol & Immunol, Coll Med, Tainan 701, Taiwan
来源：
JOURNAL OF NATURAL PRODUCTS | 1999年 / 62卷 / 07期
关键词：
D O I：
10.1021/np9900167
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two new naturally occurring 1-aryl-2,3-naphthalide lignans, cilinaphthalide A (1) and cilinaphthalide B (2), and nine known compounds were isolated from the whole plant of Justicia ciliata. Their structures were established by spectral analysis, and their cytotoxic activity was evaluated against several different cell lines. The known compound, justicidin A, showed potent cytotoxic effects against T-24, CaSki, SiHa, HT-3, PLC/PRF/5, and 212 cells in vitro.
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页码：1056 / 1058
页数：3
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