Evaluation of Nanosuspensions for Absorption Enhancement of Poorly Soluble Drugs: In Vitro Transport Studies Across Intestinal Epithelial Monolayers

被引：25

作者：

Lenhardt, T. ^{[1
]}

Vergnault, G. ^{[2
]}

Grenier, P. ^{[2
]}

Scherer, D. ^{[3
]}

Langguth, P. ^{[1
]}

机构：

[1] Johannes Gutenberg Univ Mainz, Dept Biopharmaceut & Pharmaceut Technol, D-55099 Mainz, Germany

[2] SkyePharma AG, Muttenz, Switzerland

[3] ApisPharma AG, Laufen, Switzerland

来源：

AAPS JOURNAL | 2008年 / 10卷 / 03期

关键词：

absorption; bioavailability enhancement; Caco-2; cells; low soluble drugs; nanosuspensions;

D O I：

10.1208/s12248-008-9050-7

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

[No abstract available]

引用

页码：435 / 438

页数：4

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