Plant microRNAs: Biogenesis, Homeostasis, and Degradation

被引:205
作者
Wang, Junli [1 ,2 ]
Mei, Jun [1 ,2 ]
Ren, Guodong [1 ]
机构
[1] Fudan Univ, Sch Life Sci, Inst Plant Biol, State Key Lab Genet Engn, Shanghai, Peoples R China
[2] Fudan Univ, Sch Life Sci, Inst Plant Biol, Minist Educ,Key Lab Biodivers Sci & Ecol Engn, Shanghai, Peoples R China
基金
中国国家自然科学基金;
关键词
miRNA biogenesis; DCL1; HEN1; Argonaute; target mimic; uridylation; SMALL INTERFERING RNAS; BINDING-PROTEIN HYL1; MIRNA BIOGENESIS; CYCLOPHILIN; 40; POSTTRANSCRIPTIONAL REGULATION; FUNCTIONAL-ANALYSIS; ARGONAUTE PROTEINS; NONCODING RNAS; PRI-MIRNA; 3' ENDS;
D O I
10.3389/fpls.2019.00360
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
MicroRNAs (miRNAs), a class of endogenous, tiny, non-coding RNAs, are master regulators of gene expression among most eukaryotes. Intracellular miRNA abundance is regulated under multiple levels of control including transcription, processing, RNA modification, RNA-induced silencing complex (RISC) assembly, miRNA-target interaction, and turnover. In this review, we summarize our current understanding of the molecular components and mechanisms that influence miRNA biogenesis, homeostasis, and degradation in plants. We also make comparisons with findings from other organisms where necessary.
引用
收藏
页数:12
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