Zika Virus: Immunity and Vaccine Development

被引：92

作者：

Pierson, Theodore C. ^{[1
]}

Graham, Barney S. ^{[2
]}

机构：

[1] NIAID, Viral Pathogenesis Sect, Viral Dis Lab, NIH, 9000 Rockville Pike, Bethesda, MD 20892 USA

[2] NIAID, Viral Pathogenesis Lab, Vaccine Res Ctr, NIH, 9000 Rockville Pike, Bethesda, MD 20892 USA

来源：

CELL | 2016年 / 167卷 / 03期

关键词：

WEST-NILE-VIRUS; BORNE ENCEPHALITIS-VIRUS; ANTIBODY-DEPENDENT ENHANCEMENT; CD8(+) T-CELLS; DENGUE VIRUS; ENVELOPE PROTEIN; STRUCTURAL BASIS; NEUTRALIZING ANTIBODY; CROSS-REACTIVITY; SURFACE-PROTEINS;

D O I：

10.1016/j.cell.2016.09.020

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The emergence of Zika virus in the Americas and Caribbean created an urgent need for vaccines to reduce transmission and prevent disease, particularly the devastating neurodevelopmental defects that occur in utero. Rapid advances in Zika immunity and the development of vaccine candidates provide cautious optimism that preventive measures are possible.

引用

页码：625 / 631

页数：7

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