Consequences of excess iodine

被引:424
作者
Leung, Angela M. [1 ]
Braverman, Lewis E. [2 ]
机构
[1] Univ Calif Los Angeles, David Geffen Sch Med, Dept Med, Div Endocrinol,VA Greater Los Angeles Healthcare, Los Angeles, CA 90073 USA
[2] Boston Univ, Sch Med, Dept Med, Sect Endocrinol Diabet & Nutr, Boston, MA 02118 USA
关键词
AMIODARONE-INDUCED THYROTOXICOSIS; THYROID-FUNCTION; URINARY IODINE; CONTRAST-MEDIA; SUBCLINICAL HYPOTHYROIDISM; DIETARY IODINE; POLYVINYLPYRROLIDONE-IODINE; CONGENITAL HYPOTHYROIDISM; EUTHYROID PATIENTS; SUFFICIENT AREA;
D O I
10.1038/nrendo.2013.251
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Iodine is a micronutrient that is essential for the production of thyroid hormones. The primary source of iodine is the diet via consumption of foods that have been fortified with iodine, including salt, dairy products and bread, or that are naturally abundant in the micronutrient, such as seafood. Recommended daily iodine intake is 150 mu g in adults who are not pregnant or lactating. Ingestion of iodine or exposure above this threshold is generally well-tolerated. However, in certain susceptible individuals, including those with pre-existing thyroid disease, the elderly, fetuses and neonates, or patients with other risk factors, the risk of developing iodine-induced thyroid dysfunction might be increased. Hypothyroidism or hyperthyroidism as a result of supraphysiologic iodine exposure might be either subclinical or overt, and the source of the excess iodine might not be readily apparent.
引用
收藏
页码:136 / 142
页数:7
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