Differentiated thyroid cancer in childhood: a literature update

被引：18

作者：

Karapanou, Olga ^{[1
]}

Tzanela, Marinella ^{[1
]}

Vlassopoulou, Barbara ^{[1
]}

Kanaka-Gantenbein, Christina ^{[2
]}

机构：

[1] Evangelismos Med Ctr, Dept Endocrinol Diabet & Metab, Athens, Greece

[2] Aghia Sophia Childrens Hosp, Dept Pediat 1, Div Endocrinol Metab & Diabet, Athens, Greece

来源：

HORMONES-INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM | 2017年 / 16卷 / 04期

关键词：

Differentiated thyroid cancer; Mutations; Outcome; Radiation; Recurrence; THYROGLOBULIN ANTIBODY POSITIVITY; TERM-FOLLOW-UP; RADIOIODINE TREATMENT; THYROTROPIN SUPPRESSION; MANAGEMENT GUIDELINES; DISEASE PROGRESSION; RADIOACTIVE IODINE; ADULT PATIENTS; YOUNG-ADULTS; CHILDREN;

D O I：

10.14310/horm.2002.1758

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Differentiated thyroid cancer in childhood is rare. Apart from family history, radiation exposure is a major risk factor. Although its clinical course is quite aggressive with higher rates of lymph node and pulmonary metastases as compared to adults, the final outcome tends to be favorable with mortality rates less than 2%. We herein review the clinical picture, genetic background response to treatment and recurrence rates of differentiated thyroid cancer in children and young adolescents are thoroughly reviewed and the main differences with adult differentiated thyroid cancer are highlighted.

引用

页码：381 / 387

页数：7

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