The copper-free Sonogashira cross-coupling reaction promoted by palladium complexes of nitrogen-containing chelating ligands in neat water at room temperature

被引：31

作者：

Zhong, Hong ^{[1
]}

Wang, Jinyun ^{[1
]}

Li, Liuyi ^{[1
]}

Wang, Ruihu ^{[1
]}

机构：

[1] Chinese Acad Sci, Fujian Inst Res Struct Matter, State Key Lab Struct Chem, Key Lab Coal Ethylene Glycol & Its Related Techno, Fuzhou 350002, Fujian, Peoples R China

来源：

DALTON TRANSACTIONS | 2014年 / 43卷 / 05期

关键词：

SUZUKI-MIYAURA REACTION; RECOVERABLE CATALYST; CHLORIDE COMPLEX; IONIC LIQUIDS; AQUEOUS-MEDIA; EFFICIENT; HECK; PRECATALYSTS; OXIDATION; PROTOCOL;

D O I：

10.1039/c3dt52970c

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The commercially available 2,2'-dipyridylamine was used as a supporting ligand in the palladium-catalyzed Sonogashira cross-coupling reaction. The reactions between aryl iodides and terminal alkynes with different steric hindrance can be efficiently performed in the absence of copper in neat water at room temperature. The superior catalytic performance of the catalytic system was attributed to water solubility of the palladium 2,2'-dipyridylamine complex. Palladium nanoparticles with small size and narrow size distribution were formed after the cross-coupling reaction.

引用

页码：2098 / 2103

页数：6