Regioselective introduction of 2-propynyl groups into the C-2 or C-3 position of furanoside ring

被引：3
|
作者：
Kubota, D [1 ]
Mitsunobu, O [1 ]
机构：
[1] AOYAMA GAKUIN UNIV, COLL SCI & ENGN, DEPT CHEM, SETAGAYA KU, TOKYO 157, JAPAN
来源：
CHEMISTRY LETTERS | 1997年 / 06期
关键词：
D O I：
10.1246/cl.1997.517
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The reaction of methyl 2,3-anhydro-alpha-D-ribofuranoside or methyl 2,3-anhydro-5,6-O-cyclohexylidene-alpha-D-allofuranoside with 2-propynyl metallic reagents exclusively gave the corresponding 2-C-(2-propynyl)-arabino-pentofuranosides and 2-C-(2-propynyl)-altro-hexofuranosides, respectively. In contrast, the beta-anomers were selectively attacked at the position 3 to afford the corresponding 3-C-(2-propynyl)furanosides.
引用
收藏
页码：517 / 518
页数：2
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