Primary prophylaxis of gastroesophageal variceal bleeding: consensus recommendations of the Asian Pacific Association for the Study of the Liver

被引:35
作者
Sarin, Shiv Kumar [1 ]
Kumar, Ashish [1 ]
Angus, Peter W. [1 ]
Baijal, Sanjay Saran [1 ]
Chawla, Yogesh Kumar [1 ]
Dhiman, Radha Krishna [1 ]
de Silva, H. Janaka [1 ]
Hamid, Saeed [1 ]
Hirota, Shozo [1 ]
Hou, Ming-Chih [1 ]
Jafri, Wasim [1 ]
Khan, Mobin [1 ]
Lesmana, Laurentius A. [1 ]
Lui, Hock F. [1 ]
Malhotra, Veena [1 ]
Maruyama, Hitoshi [1 ]
Mazumder, Debendranath Guha [1 ]
Omata, Masao [1 ]
Poddar, Ujjal [1 ]
Puri, Amrinder S. [1 ]
Sharma, Praveen [1 ]
Qureshi, Huma [1 ]
Raza, Rizvi Moattar [1 ]
Sahni, Peush [1 ]
Sakhuja, Puja [1 ]
Salih, Mohammad [1 ]
Santra, Amal [1 ]
Sharma, Barjesh Chander [1 ]
Shah, Hasnain Ali [1 ]
Shiha, Gamal [1 ]
Sollano, Jose [1 ]
机构
[1] Univ Delhi, GB Pant Hosp, Dept Gastroenterol, New Delhi 110002, India
关键词
Varices; Cirrhosis; GI bleed; Guidelines;
D O I
10.1007/s12072-008-9096-8
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The Asian Pacific Association for the Study of the Liver (APASL) set up a Working Party on Portal Hypertension in 2002, with a mandate to develop consensus guidelines on various clinical aspects of portal hypertension relevant to disease patterns and clinical practice in the Asia-Pacific region. Variceal bleeding is a consequence of portal hypertension, which, in turn, is the major complication of liver cirrhosis. Primary prophylaxis to prevent the first bleed from varices is one of the most important strategies for reducing the mortality in cirrhotic patients. Experts predominantly from the Asia-Pacific region were requested to identify the different aspects of primary prophylaxis and develop the consensus guidelines. The APASL Working Party on Portal Hypertension evaluated the various therapies that have been used for the prevention of first variceal bleeding. A 2-day meeting was held on January 12 and 13, 2007, at New Delhi, India, to discuss and finalize the consensus statements. Only those statements that were unanimously approved by the experts were accepted. These statements were circulated to all the experts and were subsequently presented at the annual conference of the APASL at Kyoto, Japan, in March 2007.
引用
收藏
页码:429 / 439
页数:11
相关论文
共 106 条
[91]   A randomized controlled trial of endoscopic variceal band ligation for primary prophylaxis of variceal bleeding [J].
Sarin, SK ;
Guptan, RKC ;
Jain, AK ;
Sundaram, KR .
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 1996, 8 (04) :337-342
[92]   PREVALENCE, CLASSIFICATION AND NATURAL-HISTORY OF GASTRIC VARICES - A LONG-TERM FOLLOW-UP-STUDY IN 568 PORTAL-HYPERTENSION PATIENTS [J].
SARIN, SK ;
LAHOTI, D ;
SAXENA, SP ;
MURTHY, NS ;
MAKWANA, UK .
HEPATOLOGY, 1992, 16 (06) :1343-1349
[93]  
Sarin SK, 2002, AM J GASTROENTEROL, V97, P1010
[94]  
Sarin SK, 2001, PORTAL HYPERTENSION, P76
[95]   Ligation versus propranolol for the primary prophylaxis of variceal bleeding in cirrhosis [J].
Schepke, M ;
Kleber, G ;
Nürnberg, D ;
Willert, J ;
Koch, L ;
Veltzke-Schlieker, W ;
Hellerbrand, C ;
Kuth, J ;
Schanz, S ;
Kahl, S ;
Fleig, WE ;
Sauerbruch, T .
HEPATOLOGY, 2004, 40 (01) :65-72
[96]  
SEE A, 1986, GASTROEN CLIN BIOL, V10, P604
[97]   Pantoprazole reduces the size of postbanding ulcers after variceal band ligation: A randomized, controlled trial [J].
Shaheen, NJ ;
Stuart, E ;
Schmitz, SM ;
Mitchell, KL ;
Fried, MW ;
Zacks, S ;
Russo, MW ;
Galanko, J ;
Shrestha, R .
HEPATOLOGY, 2005, 41 (03) :588-594
[98]   Propranolol in prevention of portal hypertensive hemorrhage in children: A pilot study [J].
Shashidhar, H ;
Langhans, N ;
Grand, RJ .
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 1999, 29 (01) :12-17
[99]   Efficacy and safety of balloon-occluded endoscopic injection sclerotherapy as a prophylactic treatment for high-risk gastric fundal varices: a prospective, randomized, comparative clinical trial [J].
Shiba, M ;
Higuchi, K ;
Nakamura, K ;
Itani, A ;
Kuga, T ;
Okazaki, H ;
Fujiwara, Y ;
Arakawa, T .
GASTROINTESTINAL ENDOSCOPY, 2002, 56 (04) :522-528
[100]   INTRAVASCULAR ESOPHAGEAL VARICEAL PRESSURE (IOVP) ASSESSED BY ENDOSCOPIC FINE NEEDLE PUNCTURE UNDER BASAL CONDITIONS, VALSALVAS MANEUVER AND AFTER GLYCERYLTRINITRATE APPLICATION [J].
STARITZ, M ;
PORALLA, T ;
ZUMBUSCHENFELDE, KHM .
GUT, 1985, 26 (05) :525-530