A new and convenient method of generating alkyl cyanides from alcohols and thiols using 2,4,6-trichloro[1,3,5]triazine/n-Bu4NCN

被引：7

作者：

Akhlaghinia, B ^{[1
]}

Roohi, E ^{[1
]}

机构：

[1] Damghan Univ Basic Sci, Dept Chem, Damghan, Iran

来源：

LETTERS IN ORGANIC CHEMISTRY | 2005年 / 2卷 / 08期

关键词：

2,4,6-trichloro[1,3,5] triazine(TT); alcohol; thiol; alkyl cyanide;

D O I：

10.2174/157017805774717571

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Alkyl cyanides are prepared in good to excellent yields (average yield 93%)by treatment of alcohols and thiols with 2,4,6-trichloro[1,3,5]triazine/n-Bu4NCN in refluxing acetonitrile. This method is highly selective for conversion of 1 degrees alcohols in the presence of 2 degrees and 3 degrees ones and thiols.

引用

页码：725 / 730

页数：6