A new and convenient method of generating alkyl cyanides from alcohols and thiols using 2,4,6-trichloro[1,3,5]triazine/n-Bu4NCN

被引：7
作者：
Akhlaghinia, B [1 ]
Roohi, E [1 ]
机构：
[1] Damghan Univ Basic Sci, Dept Chem, Damghan, Iran
来源：
LETTERS IN ORGANIC CHEMISTRY | 2005年 / 2卷 / 08期
关键词：
2,4,6-trichloro[1,3,5] triazine(TT); alcohol; thiol; alkyl cyanide;
D O I：
10.2174/157017805774717571
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Alkyl cyanides are prepared in good to excellent yields (average yield 93%)by treatment of alcohols and thiols with 2,4,6-trichloro[1,3,5]triazine/n-Bu4NCN in refluxing acetonitrile. This method is highly selective for conversion of 1 degrees alcohols in the presence of 2 degrees and 3 degrees ones and thiols.
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页码：725 / 730
页数：6
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