Single-visit approach of cervical cancer screening: See and Treat in Indonesia

被引：15

作者：

Vet, J. N. I. ^{[1
]}

Kooijman, J. L. ^{[1
]}

Henderson, F. C. ^{[1
]}

Aziz, F. M. ^{[3
]}

Purwoto, G. ^{[3
]}

Susanto, H. ^{[6
]}

Surya, I. G. D. ^{[7
]}

Budiningsih, S. ^{[4
]}

Cornain, S. ^{[5
]}

Fleuren, G. J. ^{[2
]}

Trimbos, J. B. ^{[1
]}

Peters, A. A. W. ^{[1
]}

机构：

[1] Leiden Univ, Med Ctr, Dept Gynaecol, NL-2300 RC Leiden, Netherlands

[2] Leiden Univ, Med Ctr, Dept Pathol, NL-2300 RC Leiden, Netherlands

[3] Univ Indonesia, Dept Gynaecol, Jakarta 10430, Indonesia

[4] Univ Indonesia, Dept Community Med, Jakarta 10430, Indonesia

[5] Univ Indonesia, Rumah Sakit Cipto Mangukusumo, Dept Anat, Jakarta 10430, Indonesia

[6] Padjadjaran State Univ, Rumah Sakit Hasan Sadikin, Dept Gynaecol, Bandung 40161, Indonesia

[7] Univ Udayana, Rumah Sakit Sanglah, Dept Gynaecol, Bali, Indonesia

来源：

BRITISH JOURNAL OF CANCER | 2012年 / 107卷 / 05期

关键词：

single-visit approach; visual inspection with acetic acid (VIA); cryotherapy; Indonesia; VISUAL INSPECTION; ACETIC-ACID; MORTALITY; PROGRAMS; TRENDS;

D O I：

10.1038/bjc.2012.334

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

BACKGROUND: We performed a cross-sectional study in Indonesia to evaluate the performance of a single-visit approach of cervical cancer screening, using visual inspection with acetic acid (VIA), histology and cryotherapy in low-resource settings. METHODS: Women having limited access to health-care facilities were screened by trained doctors using VIA. If the test was positive, biopsies were taken and when eligible, women were directly treated with cryotherapy. Follow-up was performed with VIA and cytology after 6 months. When cervical cancer was suspected or diagnosed, women were referred. The positivity rate, positive predictive value (PPV) and approximate specificity of the VIA test were calculated. The detection rate for cervical lesions was given. RESULTS: Screening results were completed in 22040 women, of whom 92.7% had never been screened. Visual inspection with acetic acid was positive in 4.4%. The PPV of VIA to detect CIN I or greater and CIN II or greater was 58.7% and 29.7%, respectively. The approximate specificity was 98.1%, and the detection rate for CIN I or greater was 2.6%. CONCLUSION: The single-visit approach cervical cancer screening performed well, showing See and Treat is a promising way to reduce cervical cancer in Indonesia. British Journal of Cancer (2012) 107, 772-777. doi:10.1038/bjc.2012.334 www.bjcancer.com Published online 31 July 2012 (C) 2012 Cancer Research UK

引用

页码：772 / 777

页数：6