Prenatal smoke (Nicotine) exposure and offspring's metabolic disease susceptibility in adulthood

被引：10
作者：
He, Bo [1 ,5 ,6 ]
Zhang, Qi [1 ,3 ]
Guo, Yu [1 ,3 ]
Ao, Ying [1 ,3 ]
Tie, Kai [2 ,3 ]
Xiao, Hao [2 ,3 ]
Chen, Liaobin [2 ,3 ]
Xu, Dan [3 ,4 ,7 ]
Wang, Hui [1 ,3 ,4 ]
机构：
[1] Basic Med Sch Wuhan Univ, Dept Pharmacol, Wuhan 430071, Peoples R China
[2] Wuhan Univ, Dept Orthoped Surg, Zhongnan Hosp, Wuhan 430071, Peoples R China
[3] Hubei Prov Key Lab Dev Originated Dis, Wuhan 430071, Peoples R China
[4] Wuhan Univ, Zhongnan Hosp, Sch Pharmaceut Sci, Dept Pharm, Wuhan 430071, Peoples R China
[5] Kunming Med Univ, Sch Pharmaceut Sci, Kunming 650500, Peoples R China
[6] Kunming Med Univ, Yunnan Key Lab Pharmacol Nat Prod, Kunming 650500, Peoples R China
[7] Zhongnan Hosp Wuhan Univ, Wuhan Univ, Sch Pharmaceut Sci, Dept Pharm,Hubei Provincial Key Lab Dev Originated, Wuhan 430071, Peoples R China
来源：
FOOD AND CHEMICAL TOXICOLOGY | 2022年 / 168卷
基金：
中国国家自然科学基金;
关键词：
Smoke; Nicotine; Intrauterine programming; Metabolic diseases; Glucocorticoids; INTRAUTERINE GROWTH-RETARDATION; LONG-TERM CONSEQUENCES; HIGH-FAT DIET; INFANT-DEATH-SYNDROME; BETA-CELL APOPTOSIS; LOW-BIRTH-WEIGHT; MATERNAL-SMOKING; CIGARETTE-SMOKING; BLOOD-PRESSURE; ADRENAL AXIS;
D O I：
10.1016/j.fct.2022.113384
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
Exposure to smoking (nicotine) during pregnancy not only directly affects fetal development, but also increases susceptibility to metabolic diseases in adulthood, but the mechanism of action remains unclear. Here, we review epidemiological and laboratory studies linking these relationships. In addition to the direct effect of nicotine on the fetus, intrauterine neuroendocrine-metabolic programming mediated by maternal glucocorticoid over-exposure also plays an important role, involving glucocorticoid-insulin-like growth factor 1 (GC-IGF1) axis, hypothalamic-pituitary-adrenal (HPA) axis, renin-angiotensin system (RAS) and other endocrine systems. Epi-genetics is involved in intrauterine neuroendocrine-metabolic programming, metabolic disease susceptibility and multigenerational inheritance. There are "two programming" and "two strikes" mechanisms for the occurrence of fetal-originated metabolic diseases in adulthood. These innovative research summaries and academic viewpoints provide experimental and theoretical basis for systematically elucidating the occurrence and development of fetal-originated metabolic diseases.
引用
收藏
页数：12
相关论文
共 147 条
[61]   Ontogeny and nutritional programming of the hepatic growth hormone-insulin-like growth factor-prolactin axis in the sheep [J].
Hyatt, Melanie A. ;
Budge, Helen ;
Walker, David ;
Stephenson, Terence ;
Symonds, Michael E. .
ENDOCRINOLOGY, 2007, 148 (10) :4754-4760
[62]   Active and passive maternal smoking during pregnancy and the risks of low birthweight and preterm birth: the Generation R Study [J].
Jaddoe, Vincent W. V. ;
Troe, Ernst-Jan W. M. ;
Hofman, Albert ;
Mackenbach, Johan P. ;
Moll, Henriette A. ;
Steegers, Eric A. P. ;
Witteman, Jacqueline C. M. .
PAEDIATRIC AND PERINATAL EPIDEMIOLOGY, 2008, 22 (02) :162-171
[63]   Fetal Exposure to Parental Smoking and the Risk of Type 2 Diabetes in Adult Women [J].
Jaddoe, Vincent W. V. ;
de Jonge, Layla L. ;
van Dam, Rob M. ;
Willett, Walter C. ;
Harris, Holly ;
Stampfer, Meir J. ;
Hu, Frank B. ;
Michels, Karin B. .
DIABETES CARE, 2014, 37 (11) :2966-2973
[64]   Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals [J].
Jaenisch, R ;
Bird, A .
NATURE GENETICS, 2003, 33 (Suppl 3) :245-254
[65]   Morphological and biological effects of maternal exposure to tobacco smoke on the feto-placental unit [J].
Jauniaux, Eric ;
Burton, Graham J. .
EARLY HUMAN DEVELOPMENT, 2007, 83 (11) :699-706
[66]   Role of IGF signaling in catch-up growth and accelerated temporal development in zebrafish embryos in response to oxygen availability [J].
Kamei, Hiroyasu ;
Ding, Yonghe ;
Kajimura, Shingo ;
Wells, Michael ;
Chiang, Peter ;
Duan, Cunming .
DEVELOPMENT, 2011, 138 (04) :777-786
[67]   Prenatal smoking exposure and cardio-metabolic risk factors in adulthood: a general population study and a meta-analysis [J].
Kataria, Yachana ;
Gaewsky, Lyvia ;
Ellervik, Christina .
INTERNATIONAL JOURNAL OF OBESITY, 2019, 43 (04) :763-773
[68]   Prolonged endoplasmic reticulum stress alters placental morphology and causes low birth weight [J].
Kawakami, Takashige ;
Yoshimi, Masaki ;
Kadota, Yoshito ;
Inoue, Masahisa ;
Sato, Masao ;
Suzuki, Shinya .
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2014, 275 (02) :134-144
[69]   A conserved regulatory system for aging [J].
Kenyon, C .
CELL, 2001, 105 (02) :165-168
[70]   Metabolic syndrome and development of diabetes mellitus: Application and validation of recently suggested definitions of the metabolic syndrome in a prospective cohort study [J].
Laaksonen, DE ;
Lakka, HM ;
Niskanen, LK ;
Kaplan, GA ;
Salonen, JT ;
Lakka, TA .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 2002, 156 (11) :1070-1077
234567891011