Accuracy in melanoma detection: A 10-year multicenter survey

被引：140

作者：

Argenziano, Giuseppe ^{[1
]}

Cerroni, Lorenzo ^{[2
]}

Zalaudek, Iris ^{[2
]}

Staibano, Stefania ^{[3
]}

Hofmann-Wellenhof, Rainer ^{[2
]}

Arpaia, Nicola ^{[4
]}

Bakos, Renato Marchiori ^{[5
]}

Balme, Brigitte ^{[6
]}

Bandic, Jadran ^{[7
]}

Bandelloni, Roberto ^{[8
,9
]}

Brunasso, Alexandra M. G. ^{[8
,9
]}

Cabo, Horacio ^{[10
]}

Calcara, David A. ^{[11
]}

Carlos-Ortega, Blanca ^{[12
]}

Carvalho, Ana Carolina ^{[13
]}

Casas, Gabriel ^{[14
]}

Dong, Huiting ^{[15
]}

Ferrara, Gerardo ^{[16
]}

Filotico, Raffaele ^{[4
]}

Gomez, Guillermo ^{[17
]}

Halpern, Allan ^{[18
]}

Ilardi, Gennaro ^{[3
]}

Ishiko, Akira ^{[19
]}

Kandiloglu, Gulsen ^{[20
]}

Kawasaki, Hiroshi ^{[19
]}

Kobayashi, Ken ^{[21
]}

Koga, Hiroshi ^{[22
]}

Kovalyshyn, Ivanka ^{[18
]}

Langford, David ^{[23
]}

Liu, Xin ^{[24
]}

Marghoob, Ashfaq A. ^{[18
]}

Mascolo, Massimo ^{[3
]}

Massone, Cesare ^{[2
]}

Mazzoni, Laura ^{[25
]}

Menzies, Scott ^{[13
]}

Minagawa, Akane ^{[22
]}

Nugnes, Loredana ^{[3
]}

Ozdemir, Fezal ^{[26
]}

Pellacani, Giovanni ^{[27
]}

Seidenari, Stefania ^{[27
]}

Siamas, Katherine ^{[18
]}

Stanganelli, Ignazio ^{[25
]}

Stoecker, William V. ^{[11
]}

Tanaka, Masaru ^{[21
]}

Thomas, Luc ^{[6
]}

Tschandl, Philipp ^{[28
]}

Kittler, Harald ^{[28
]}

机构：

[1] Arcispedale Santa Maria Nuova, Dept Med, Dermatol Unit, I-42100 Reggio Emilia, Italy

[2] Med Univ Graz, Dept Dermatol, Graz, Austria

[3] Univ Naples Federico II, Pathol Sect, Dept Biomorphol & Funct Sci, Naples, Italy

[4] Univ Bari, Dept Internal Med Immunol & Infect Dis, Unit Dermatol 2, Bari, Italy

[5] Univ Fed Rio Grande do Sul, Dept Dermatol, Porto Alegre, RS, Brazil

[6] Univ Lyon 1, Ctr Hosp Lyon Sud, Dept Dermatol, Pierre Benite, France

[7] ORS Hosp Belgrade, Special Hosp Plast & Reconstruct Surg, Skin Canc Unit, Belgrade, Serbia

[8] Galliera Hosp, Dept Pathol, Genoa, Italy

[9] Galliera Hosp, Dept Dermatol, Genoa, Italy

[10] Univ Buenos Aires, Dermatol Sect, Inst Invest Med Lanari, Buenos Aires, DF, Argentina

[11] Dermatol Ctr, Rolla, MO USA

[12] Hosp Especialidades Ctr Med La Raza, Ctr Med Nacl La Raza, Dept Dermatol, Mexico City, DF, Mexico

[13] Univ Sydney, Sydney Med Sch, Sydney Melanoma Diagnost Ctr, Royal Prince Alfred Hosp, Camperdown, NSW, Australia

[14] Hosp Aleman, Buenos Aires, DF, Argentina

[15] Zhengzhou Univ, Dept Dermatol, Teaching Hosp 1, Zhengzhou, Henan Province, Peoples R China

[16] Gaetano Rummo Gen Hosp, Anat Pathol Unit, Benevento, Italy

[17] Hosp Especialidades Ctr Med La Raza, Ctr Med Nacl La Raza, Dept Pathol, Mexico City, DF, Mexico

[18] Mem Sloan Kettering Canc Ctr, New York, NY 10021 USA

[19] Keio Univ, Tokyo, Japan

[20] Univ Ege, Fac Med, Dept Pathol, Bornova, Turkey

[21] Tokyo Womens Med Univ, Med Ctr E, Dept Dermatol, Tokyo, Japan

[22] Shinshu Univ, Dept Dermatol, Matsumoto, Nagano 390, Japan

[23] Aikmans Rd Clin, Merivale Christchurch, New Zealand

[24] Henan Gen Coal Grp Corp, Yongcheng Coal Grp Corp, Gen Hosp, Dept Dermatol, Yongcheng, Henan Province, Peoples R China

[25] Ist Sci Romagnolo Studio & Cura Tumori, Skin Canc Unit, Meldola, Forli Cesena, Italy

[26] Univ Ege, Fac Med, Dept Dermatol, Bornova, Turkey

[27] Univ Modena & Reggio Emilia, Dept Dermatol, Modena, Italy

[28] Med Univ Vienna, Div Gen Dermatol, Dept Dermatol, Vienna, Austria

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2012年 / 67卷 / 01期

关键词：

clinical diagnosis; dermatoscopy; melanoma; number needed to excise; skin cancer; NAKED-EYE EXAMINATION; PIGMENTED LESIONS; SKIN-LESIONS; PRIMARY-CARE; DERMOSCOPY; NUMBER;

D O I：

10.1016/j.jaad.2011.07.019

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Background: Early excision is the only strategy to reduce melanoma mortality, but unnecessary excision of benign lesions increases morbidity and healthcare costs. Objective: To assess accuracy in melanoma detection based on number-needed-to-excise (NNE) values over a 10-year period. Methods: Information was retrieved on all histopathologically confirmed cutaneous melanomas or melanocytic nevi that were excised between 1998 and 2007 at participating clinics. NNE values were calculated by dividing the total number of excised lesions by the number of melanomas. Analyses included changes in NNE over time, differences in NNE between specialized clinical settings (SCS) versus non-specialized clinical settings (NSCS), and patient factors influencing NNE. Results: The participating clinics contributed a total of 300,215 cases, including 17,172 melanomas and 283,043 melanocytic nevi. The overall NNE values achieved in SCS and NSCS in the 10-year period were 8.7 and 29.4, respectively. The NNE improved over time in SCS (from 12.8 to 6.8), but appeared unchanged in NSCS. Most of the effect on NNE in SCS was due to a greater number of excised melanomas. Higher NNE values were observed in patients younger than 40 years and for lesions located on the trunk. Limitations: No data concerning the use of dermatoscopy and digital monitoring procedures were collected from the participating centers. Conclusion: Over the 10-year study period, accuracy in melanoma detection improved only in specialized clinics maybe because of a larger use of new diagnostic techniques such as dermatoscopy. (J Am Acad Dermatol 2012;67:54-9.)

引用

页码：54 / U274

页数：7

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