Scanning fiber angle-resolved low coherence interferometry

被引:12
作者
Zhu, Yizheng [1 ]
Terry, Neil G. [1 ]
Wax, Adam [1 ]
机构
[1] Duke Univ, Dept Biomed Engn, Durham, NC 27708 USA
基金
美国国家卫生研究院;
关键词
SCATTERING SPECTROSCOPY; CANCER; CELLS;
D O I
10.1364/OL.34.003196
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We present a fiber-optic probe for Fourier-domain angle-resolved low coherence interferometry for the determination of depth-resolved scatterer size. The probe employs a scanning single-mode fiber to collect the angular scattering distribution of the sample, which is analyzed using the Mie theory to obtain the average size of the scatterers. Depth sectioning is achieved with low coherence Mach-Zehnder interferometry. In the sample arm of the interferometer, a fixed fiber illuminates the sample through an imaging lens and a collection fiber samples the backscattered angular distribution by scanning across the Fourier plane image of the sample. We characterize the optical performance of the probe and demonstrate the ability to execute depth-resolved sizing with subwavelength accuracy by using a double-layer phantom containing two sizes of polystyrene microspheres. (C) 2009 Optical Society of America
引用
收藏
页码:3196 / 3198
页数:3
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