Pharmacological Management of Chemotherapy-Induced Nausea and Vomiting in Children with Cancer

被引：11

作者：

Cefalo, M. G. ^{[1
]}

Ruggiero, A. ^{[1
]}

Maurizi, P. ^{[1
]}

Attina, G. ^{[1
]}

Arlotta, A. ^{[1
]}

Riccardi, R. ^{[1
]}

机构：

[1] Univ Cattolica Sacro Cuore, Div Pediat Oncol, I-00168 Rome, Italy

来源：

JOURNAL OF CHEMOTHERAPY | 2009年 / 21卷 / 06期

关键词：

Nausea; vomiting; chemotherapy; children; antiemetic agents; MODERATELY EMETOGENIC CHEMOTHERAPY; CISPLATIN-INDUCED EMESIS; ANTIEMETIC THERAPY; DOUBLE-BLIND; NEUROKININ-1; ANTAGONIST; PEDIATRIC ONCOLOGY; PHASE-III; APREPITANT; PREVENTION; ONDANSETRON;

D O I：

10.1179/joc.2009.21.6.605

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Nausea and vomiting are respectively the first and third most relevant chemotherapy-associated side effects in pediatric oncology, despite the introduction of new antiemetic agents. Symptoms change according to the antineoplastic agents used, and are influenced by age since emotional and psychological aspects play an important role. Studies conducted on new antiemetic therapies usually focus on adult populations affected by tumors, whereas there are very few series including pediatric patients, who are even more severely affected by this specific side effect.

引用

页码：605 / 610

页数：6