Organoselenium compounds based on substituted acetanilides: Synthesis, characterization and antioxidant activity

被引：0

作者：

Phadnis, Prasad P. ^{[1
]}

Hodage, Ananda S. ^{[1
]}

Priyadarsini, K. I. ^{[2
]}

Jain, Vimal K. ^{[1
]}

机构：

[1] Bhabha Atom Res Ctr, Div Chem, Bombay 400085, Maharashtra, India

[2] Bhabha Atom Res Ctr, Radiat & Photochem Div, Bombay 400085, Maharashtra, India

来源：

INDIAN JOURNAL OF CHEMISTRY SECTION A-INORGANIC BIO-INORGANIC PHYSICAL THEORETICAL & ANALYTICAL CHEMISTRY | 2014年 / 53卷 / 01期

关键词：

Coordination chemistry; Organoselenium compounds; Acetanilides; Antioxidant activity; Selenium; NUCLEAR-MAGNETIC-RESONANCE; OXIDATIVE STRESS; FREE-RADICALS; DISELENIDES; DISEASE; REACTIVITY; CHEMISTRY; CONSTANTS; SELENOLS; DESIGN;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of organoselenium compounds based on substituted acetanilides of compositions, Se{(CH2)(n)CONHC6H4X}(2) (n = 1, 2) and (SeCH2CH2CONHC6H4X)(2) (X = OW/ NH2) have been synthesized and characterized by microanalyses, IR, NMR (H-1, C-13{H-1}, (77)se{H-1}) spectroscopy and mass spectrometry. Antioxidant activity of these compounds has been evaluated against DPPH radicals in vitro. Some of these compounds exhibit better inhibition of DPPH radicals than standard BHT. The selenide, analogous to paracetamol, (p-HOC6H4NHCOCH2)(2)Se, exhibits the highest antioxidant capacity in a given series.

引用

页码：34 / 40

页数：7

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