CARCINOMA-ASSOCIATED RETINOPATHY-AN ELECTROPHYSIOLOGICAL AND IMMUNOHISTOCHEMICAL CORRELATION

被引：6

作者：

Link, Barbara ^{[1
]}

Schloetzer-Schrehardt, Ursula ^{[1
]}

Juenemann, Anselm ^{[1
]}

机构：

[1] Univ Erlangen Nurnberg, Dept Ophthalmol, D-8520 Erlangen, Germany

来源：

RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES | 2009年 / 29卷 / 01期

关键词：

carcinoma-associated retinopathy; electrophysiology; immunohistochemistry; CANCER-ASSOCIATED RETINOPATHY; RECOVERIN; ANTIBODIES; LUNG;

D O I：

10.1097/IAE.0b013e3181853d06

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Purpose: To correlate the clinical, electrophysiological, and immunohistochemical findings in patients suffering from carcinoma-associated retinopathy. Methods: Four patients with visual loss were included in this retrospective, observational consecutive case series. Electrophysiology and immunohistochemical analysis were performed to confirm the diagnosis of carcinoma-associated retinopathy. Results: Immunohistochemistry revealed a marked interindividual variability of antibody reactions against different retinal cell layers of individual patients. The electrophysiological changes corresponded to the respective immunohistochemical findings. Conclusion: Carcinoma-associated retinopathy is a heterogeneous disease, caused by different antiretinal antibodies and leading to different electrophysiological abnormalities. Diagnosis should not be delayed as undetected and thus untreated malignancy can be the cause.

引用

页码：69 / 72

页数：4

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