BEReX: Biomedical Entity-Relationship eXplorer

被引：7

作者：

Jeon, Minji ^{[1
]}

Lee, Sunwon ^{[2
]}

Lee, Kyubum ^{[2
]}

Tan, Aik-Choon ^{[3
]}

Kang, Jaewoo ^{[1
,2
]}

机构：

[1] Korea Univ, Interdisciplinary Grad Program Bioinformat, Seoul, South Korea

[2] Korea Univ, Dept Comp Sci & Engn, Seoul, South Korea

[3] Univ Colorado, Dept Med Med Oncol, Aurora, CO USA

来源：

BIOINFORMATICS | 2014年 / 30卷 / 01期

基金：

新加坡国家研究基金会;

关键词：

KINASE; IMATINIB;

D O I：

10.1093/bioinformatics/btt598

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Biomedical Entity-Relationship eXplorer (BEReX) is a new biomedical knowledge integration, search and exploration tool. BEReX integrates eight popular databases (STRING, DrugBank, KEGG, PhamGKB, BioGRID, GO, HPRD and MSigDB) and delineates an integrated network by combining the information available from these databases. Users search the integrated network by entering key words, and BEReX returns a sub-network matching the key words. The resulting graph can be explored interactively. BEReX allows users to find the shortest paths between two remote nodes, find the most relevant drugs, diseases, pathways and so on related to the current network, expand the network by particular types of entities and relations and modify the network by removing or adding selected nodes. BEReX is implemented as a standalone Java application.

引用

页码：135 / 136

页数：2

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