Facile fabrication of graphene oxide loaded with silver nanoparticles as antifungal materials

被引：18

作者：

Cui, Jianghu ^{[1
]}

Yang, Yunhua ^{[2
]}

Zheng, Mingtao ^{[3
]}

Liu, Yingliang ^{[3
]}

Xiao, Yong ^{[3
]}

Lei, Bingfu ^{[3
]}

Chen, Wei ^{[4
]}

机构：

[1] Guangdong Inst Ecoenvironm & Soil Sci, Guangdong Key Lab Agr Environm Pollut Integrated, Guangzhou 510650, Guangdong, Peoples R China

[2] Guangdong Inst Microbiol, State Key Lab Appl Microbiol Southern China, Guangdong Prov Key Lab Microbial Culture Collect, Guangzhou 510070, Guangdong, Peoples R China

[3] South China Agr Univ, Dept Appl Chem, Guangzhou 510642, Guangdong, Peoples R China

[4] Univ Texas Arlington, Dept Phys, Arlington, TX 76019 USA

来源：

MATERIALS RESEARCH EXPRESS | 2014年 / 1卷 / 04期

基金：

中国国家自然科学基金;

关键词：

graphene oxide; silver nanoparticles; antifungal; oxidative stress; apoptosis; hemolysis; PHOTOTHERMAL THERAPY; ANTIBACTERIAL; TOXICITY; EPIDEMIOLOGY; CYTOTOXICITY; NANOSPHERES; REDUCTION; EFFICACY; CELLS; IONS;

D O I：

10.1088/2053-1591/1/4/045007

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Graphene oxide loaded silver nanoparticles (GO-Ag) were synthesized using a simple method. Our evidence showed that silver nanoparticles (Ag NPs) were successfully loaded on the surface of graphene oxide sheets. The antifungal property of GO-Ag composites was investigated. The results revealed that the obtained GO-Ag composites exhibit enhanced antifungal property in comparison with that of Ag NPs. The toxicity of GO-Ag and Ag NPs were systematically evaluated. The study of cell viability, lactate dehydrogenase, reactive oxygen species, apoptosis/necrosis and hemolysis revealed that GO-Ag composites have lower cytotoxicity and better blood compatibility than Ag NPs. Therefore, these findings provide nanotoxicological information regarding GO-Ag composites which may be alternative antifungal materials in their application of biomedical fields.

引用

页数：16

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